Wei Guanyun, Qin Sheng, Li Wenjuan, Chen Liming, Ma Fei
IEEE/ACM Trans Comput Biol Bioinform. 2016 Nov 1;13(6):1155-1160. doi: 10.1109/TCBB.2015.2511767. Epub 2015 Dec 23.
MicroRNAs are crucial regulators of gene expression at post-transcriptional level. Understanding origin and evolution of miRNAs and their functions. Transposable elements (TEs) provide a natural mechanism for the origin of new miRNAs derived from TEs (MDTEs) were collected to contruct a database named MDTE database (MDTE DB) for storing, searching and analyzing MDTEs. The database proveds a convenient source for studying the origin and evolution of miRNAs.
微小RNA是转录后水平基因表达的关键调节因子。了解微小RNA的起源、进化及其功能。转座元件(TEs)为新的微小RNA(源自TEs的微小RNA,即MDTEs)的起源提供了一种自然机制,收集MDTEs构建了一个名为MDTE数据库(MDTE DB)的数据库,用于存储、搜索和分析MDTEs。该数据库为研究微小RNA的起源和进化提供了便利的资源。