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本文引用的文献

1
Positive allosteric modulation of A adenosine receptors as a novel and promising therapeutic strategy for anxiety.A 型腺苷受体的正变构调节作为一种治疗焦虑症的新型且有前景的治疗策略。
Neuropharmacology. 2016 Dec;111:283-292. doi: 10.1016/j.neuropharm.2016.09.015. Epub 2016 Sep 14.
2
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?腺嘌呤核苷作为人类疾病中的多信号守护天使：它在何时、何地以及如何发挥其保护作用？
Trends Pharmacol Sci. 2016 Jun;37(6):419-434. doi: 10.1016/j.tips.2016.02.006. Epub 2016 Mar 2.
3
TRR469, a potent A(1) adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice.TRR469是一种强效的A(1) 腺苷受体变构调节剂，在小鼠急性和神经性疼痛模型中表现出抗伤害感受特性。
Neuropharmacology. 2014 Jun;81:6-14. doi: 10.1016/j.neuropharm.2014.01.028. Epub 2014 Jan 31.
4
Allosteric enhancers of A1 adenosine receptors: state of the art and new horizons for drug development.A1 腺苷受体的变构增强剂：药物研发的现状和新领域。
Curr Med Chem. 2010;17(30):3488-502. doi: 10.2174/092986710792927831.
5
Activation of adenosine A1 receptors reduces anxiety-like behavior during acute ethanol withdrawal (hangover) in mice.腺苷A1受体的激活可减轻小鼠急性乙醇戒断（宿醉）期间的焦虑样行为。
Neuropsychopharmacology. 2006 Oct;31(10):2210-20. doi: 10.1038/sj.npp.1301001. Epub 2006 Jan 11.
6
Cognitive and sedative effects of benzodiazepine use.苯二氮䓬类药物使用的认知及镇静作用
Curr Pharm Des. 2002;8(1):45-58. doi: 10.2174/1381612023396654.
7
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.缺乏腺苷A1受体的小鼠出现痛觉过敏、焦虑及缺氧神经保护作用减弱。
Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9407-12. doi: 10.1073/pnas.161292398. Epub 2001 Jul 24.

Anxiolytic properties of A1 adenosine receptor PAMs.

作者信息

Vincenzi Fabrizio, Borea Pier Andrea, Varani Katia

机构信息

Department of Medical Sciences, Pharmacology Section, University of Ferrara, Ferrara, Italy.

出版信息

Oncotarget. 2017 Jan 31;8(5):7216-7217. doi: 10.18632/oncotarget.13802.

DOI:10.18632/oncotarget.13802
PMID:28055953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5352310/
Abstract
摘要