Zhang Y C, Cao Y F, Yang Y C, Tang R H, Yang S J, Li L, Yao S T, Ye R H, Wang J B, Duan S, He N
Department of Epidemiology, School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China.
Dehong Prefecture Center for Disease Control and Prevention, Mangshi 678400, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Jan 6;51(1):76-81. doi: 10.3760/cma.j.issn.0253-9624.2017.01.015.
To study the prevalence and correlates of unprotected sexual intercourse within HIV serodiscordant couples in Dehong prefecture, Yunnan Province, China, in 2014. This study was based on the follow-up investigation of "the AIDS cohort of seronegative spouses of HIV-infected individuals in Dehong prefecture" in 2014. The 1 520 participants were HIV seronegative spouses from all five counties/cities of Dehong prefecture who voluntarily participated in the cohort. Inclusion criteria included: having a HIV-positive spouse; ≥16 years of age; having had sexual intercourse with spouse in the past year; and being a resident of Dehong prefecture. Information on HIV-positive spouses were also collected through the local AIDS epidemic database. Chi square analysis was performed to compare differences in the rates of unprotected sexual intercourse between participants with different characteristics and lifestyle choices. Multivariable logistic regression model analysis was performed to determine correlates with unprotected sexual intercourse. The 1 520 participants had a mean age of 38.7±9.4, compared with 39.7±8.9 for their HIV-positive spouses. Among the HIV-positive spouses, 77.8% (1 183/1 520) had been infected for more than 3 years, and 87.6% (1 332/1 520) had received antiretroviral therapy. The prevalence of unprotected sexual intercourse within serodiscordant couples over the past 12 months was 16.1% (244/1 520). The prevalence of unprotected sexual intercourse correlated with the level of education of HIV-negative spouses (illiterate . middle school and above, 1.58, 0.044), the number of years since diagnosis of HIV-positive spouses (short . long, 1.6, 0.006), antiretroviral therapy of HIV-positive spouses (no . yes, 2.78, <0.001), the frequency of sexual intercourse per month (high . low, 1.66, 0.019), and whether the couple had children (no . yes, 1.72, 0.007). The prevalence of unprotected sexual intercourse within serodiscordant couples in Dehong prefecture was relatively high in 2014. Factors found to correlate with the occurrence of unprotected sexual intercourse within these couples included illiteracy of HIV-negative spouses, short time since diagnosis of HIV-positive spouses and lack of antiretroviral therapy, high frequency of sexual intercourse and no children.
为研究2014年中国云南省德宏州HIV血清学不一致夫妻中无保护性行为的流行情况及其相关因素。本研究基于2014年“德宏州HIV感染者血清学阴性配偶艾滋病队列”的随访调查。1520名参与者为德宏州所有五个县/市自愿参加该队列的HIV血清学阴性配偶。纳入标准包括：有HIV阳性配偶；年龄≥16岁；过去一年与配偶有过性行为；以及是德宏州居民。还通过当地艾滋病疫情数据库收集了HIV阳性配偶的信息。采用卡方分析比较不同特征和生活方式选择的参与者之间无保护性行为发生率的差异。进行多变量逻辑回归模型分析以确定与无保护性行为相关的因素。1520名参与者的平均年龄为38.7±9.4岁，其HIV阳性配偶的平均年龄为39.7±8.9岁。在HIV阳性配偶中，77.8%（1183/1520）感染超过3年，87.6%（1332/1520）接受过抗逆转录病毒治疗。在过去12个月中，血清学不一致夫妻中无保护性行为的发生率为16.1%（244/1520）。无保护性行为的发生率与HIV阴性配偶的教育程度（文盲.初中及以上，1.58，0.044）、HIV阳性配偶确诊后的年数（短.长，1.6，0.006）、HIV阳性配偶的抗逆转录病毒治疗情况（否.是，2.78，<0.001）、每月性行为频率（高.低，1.66，0.019）以及夫妻是否有子女（否.是，1.72，0.007）相关。2014年德宏州血清学不一致夫妻中无保护性行为的发生率相对较高。发现与这些夫妻中无保护性行为发生相关的因素包括HIV阴性配偶文盲、HIV阳性配偶确诊时间短且未接受抗逆转录病毒治疗、性行为频率高以及无子女。
