Small Christina, Kramer Holly J, Griffin Karen A, Vellanki Kavitha, Leehey David J, Bansal Vinod K, Markossian Talar W
Department of Public Health Sciences, Loyola University Chicago, 2160 S. First Ave, Maywood, IL, 60153, USA.
Division of Nephrology and Hypertension, Loyola University Medical Center, Maywood, IL, USA.
BMC Nephrol. 2017 Jan 5;18(1):3. doi: 10.1186/s12882-016-0432-2.
Previous studies have documented the high costs of non-dialysis dependent chronic kidney disease (CKD) but out-of-pocket healthcare expenditures remain poorly explored. This study described total direct and out-of-pocket expenditures for adults with non-dialysis dependent CKD and compared expenditures with those for cancer or stroke.
This study used data from the 2011-2013 Medical Expenditure Panel Survey, a national survey of healthcare expenditures in the U.S.
Expenditures were determined for adults with the following chronic diseases: CKD defined by 585 ICD9 codes (n = 52), cancer (colon, breast or bronchus/lung) (n = 870), or stroke (n = 1104). These represent adults who were aware of their conditions or visited a healthcare provider for the condition during the study period. Generalized linear models were used to estimate the marginal effects of CKD, cancer or stroke on adjusted expenditures compared to adults without CKD, cancer or stroke (n = 72,241) while controlling for demographics and co-morbidities and incorporating the sample weights of the complex survey design.
The mean age for group with CKD, cancer or stroke was 65.5, 66.1, and 68.2 years, respectively, while mean age for group without CKD, cancer or stroke was 47.8 years. Median values of total direct and out of pocket healthcare expenditures ranged from as high as $12,877 (Interquartile Range [IQR] $5031-$19,710) and $1439 ($688-$2732), respectively, with CKD, to as low as $1189 (IQR $196-$4388) and $226 (IQR $20-$764) in the group without CKD, cancer or stroke. After adjusting for demographics and comorbidities, the adjusted difference in total direct healthcare expenditures was $4746 (95% CI $1775-$7718) for CKD, $8608 (95% CI $6167-$11,049) for cancer and $5992 (95% CI $4208-$7775) for stroke vs. group without CKD, cancer or stroke. Adjusted difference in out-of-pocket healthcare expenditures was highest for adults with CKD ($760; 95% CI 0-$1745) and was larger than difference noted for cancer ($419; 95% CI 158-679) or stroke ($246; 95% CI 87-406) relative to group without CKD, cancer or stroke.
Total and out of pocket health expenditures for adults with non-dialysis dependent CKD are high and may be equal to or higher than expenditures incurred by adults with cancer or stroke.
既往研究记录了非透析依赖性慢性肾脏病(CKD)的高昂成本,但自付医疗费用仍未得到充分研究。本研究描述了非透析依赖性CKD成人的总直接费用和自付费用,并将这些费用与癌症或中风患者的费用进行比较。
本研究使用了2011 - 2013年医疗支出面板调查的数据,这是一项关于美国医疗支出的全国性调查。
确定了患有以下慢性疾病的成年人的费用:由585个ICD9编码定义的CKD(n = 52)、癌症(结肠癌、乳腺癌或支气管/肺癌)(n = 870)或中风(n = 1104)。这些代表了在研究期间知晓自身病情或因该病情就诊于医疗服务提供者的成年人。使用广义线性模型估计CKD、癌症或中风与无CKD、癌症或中风的成年人(n = 72,241)相比,对调整后费用的边际效应,同时控制人口统计学和合并症,并纳入复杂调查设计的样本权重。
CKD组、癌症组或中风组的平均年龄分别为65.5岁、66.1岁和68.2岁,而无CKD、癌症或中风组的平均年龄为47.8岁。总直接医疗费用和自付医疗费用的中位数分别高达12,877美元(四分位间距[IQR]为5031 - 19,710美元)和1439美元(IQR为688 - 2732美元)(CKD组),低至1189美元(IQR为196 - 4388美元)和226美元(IQR为20 - 764美元)(无CKD、癌症或中风组)。在调整人口统计学和合并症后,与无CKD、癌症或中风组相比,CKD患者的总直接医疗费用调整差异为4746美元(95%CI为1775 - 7718美元),癌症患者为8608美元(95%CI为6167 - 11,049美元),中风患者为5992美元(95%CI为4208 - 7775美元)。CKD成人的自付医疗费用调整差异最高(760美元;95%CI为0 - 1745美元),相对于无CKD、癌症或中风组,其差异大于癌症患者(419美元;95%CI为158 - 679美元)或中风患者(246美元;95%CI为87 - 406美元)。
非透析依赖性CKD成人的总医疗费用和自付医疗费用很高,可能等于或高于癌症或中风成人的费用。