原发性单侧肾上腺NK/T细胞淋巴瘤病例报告：三联疗法取得良好临床疗效
A case report of primary unilateral adrenal NK/T cell lymphoma: good clinical outcome with trimodality treatment.
作者信息
Hu Liu, Xu Weimin, Wang Mingwei, Wang Pan, Han Guang, Lin Chi
机构信息
Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, China.
Department of ENT, Wuhan Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430034, China.
出版信息
BMC Cancer. 2017 Jan 5;17(1):15. doi: 10.1186/s12885-016-3019-1.
BACKGROUND
Primary natural killer (NK)/T cell lymphoma of adrenal glands is an extremely rare tumor with aggressive clinical behavior. There have only been a few cases reported worldwide and the highest reported survival was 90 days. We report the first case of primary unilateral adrenal NK/T cell lymphoma in China with good outcome.
CASE PRESENTATION
This is a 28-year-old man who presented with abdominal pain and was found to have a large mass on the left adrenal and the top of the renal region. The patient underwent surgical resection and the pathology revealed primary adrenal NK/T cell lymphoma. He received adjuvant sandwich therapy encompassing sequential chemotherapy, radiotherapy and chemotherapy. The patient remains clinically and symptomatically disease-free with over two years follow up.
CONCLUSION
Given the rarity of this disease, there is limited experience with regard to its diagnosis and treatment. This case report will add to the scant literature on this tumor and will be useful for the differential diagnosis and treatment of adrenal disease.
背景
原发性肾上腺自然杀伤（NK）/T细胞淋巴瘤是一种极其罕见的肿瘤，临床行为具有侵袭性。全球仅报道过少数病例，报道的最高生存期为90天。我们报告中国首例原发性单侧肾上腺NK/T细胞淋巴瘤且预后良好的病例。
病例介绍
这是一名28岁男性，因腹痛就诊，检查发现左肾上腺及肾区顶部有一巨大肿块。患者接受了手术切除，病理显示为原发性肾上腺NK/T细胞淋巴瘤。他接受了辅助夹心治疗，包括序贯化疗、放疗和化疗。经过两年多的随访，患者临床和症状上均无疾病复发。
结论
鉴于这种疾病的罕见性，其诊断和治疗经验有限。本病例报告将补充关于该肿瘤的稀少文献，并有助于肾上腺疾病的鉴别诊断和治疗。
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