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Dasatinib and allogeneic stem cell transplantation enable sustained response in an elderly patient with -positive acute lymphoblastic leukemia.

作者信息

Frech Miriam, Jehn Lutz B, Stabla Kathleen, Mielke Stephan, Steffen Björn, Einsele Hermann, Metzelder Stephan K, Neubauer Andreas

机构信息

Department of Internal Medicine and Hematology, Oncology and Immunology, Philipps University Marburg, and University Hospital Giessen and Marburg, Baldingerstrasse, Germany.

Department of Internal Medicine II, University Hospital Würzburg, Oberdürrbacher Straβe 6, Germany.

出版信息

Haematologica. 2017 Apr;102(4):e160-e162. doi: 10.3324/haematol.2016.160531. Epub 2017 Jan 5.

DOI:10.3324/haematol.2016.160531
PMID:28057740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5395131/
Abstract
摘要

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本文引用的文献

1
Management of Philadelphia chromosome-positive acute lymphoblastic leukemia.费城染色体阳性急性淋巴细胞白血病的管理
Leuk Suppl. 2012 Aug;1(Suppl 2):S7-9. doi: 10.1038/leusup.2012.7. Epub 2012 Aug 9.
2
Imatinib-induced long-term remission in a relapsed RCSD1-ABL1-positive acute lymphoblastic leukemia.伊马替尼诱导复发的RCSD1-ABL1阳性急性淋巴细胞白血病长期缓解。
Haematologica. 2016 Aug;101(8):e332-5. doi: 10.3324/haematol.2015.139568. Epub 2016 Apr 28.
3
Drug response profiling can predict response to ponatinib in a patient with t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia.药物反应谱分析可预测一名患有t(1;9)(q24;q34)相关B细胞急性淋巴细胞白血病的患者对波纳替尼的反应。
Blood Cancer J. 2015 Mar 13;5(3):e292. doi: 10.1038/bcj.2015.13.
4
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.Ph 样急性淋巴细胞白血病中可靶向的激酶激活病变。
N Engl J Med. 2014 Sep 11;371(11):1005-15. doi: 10.1056/NEJMoa1403088.
5
Acute lymphoblastic leukemia associated with RCSD1-ABL1 novel fusion gene has a distinct gene expression profile from BCR-ABL1 fusion.与RCSD1-ABL1新型融合基因相关的急性淋巴细胞白血病具有与BCR-ABL1融合不同的基因表达谱。
Leukemia. 2013 Jun;27(6):1422-4. doi: 10.1038/leu.2012.332. Epub 2012 Nov 20.
6
RCSD1-ABL1-positive B lymphoblastic leukemia is sensitive to dexamethasone and tyrosine kinase inhibitors and rapidly evolves clonally by chromosomal translocations.RCSD1-ABL1 阳性 B 淋巴母细胞白血病对地塞米松和酪氨酸激酶抑制剂敏感，并通过染色体易位迅速克隆进化。
Int J Hematol. 2011 Sep;94(3):255-260. doi: 10.1007/s12185-011-0910-z. Epub 2011 Aug 24.
7
Chromosomal translocation t(1;9)(q24;q34) in acute lymphoblastic leukemia patient involving the ABL1 gene.急性淋巴细胞白血病患者中涉及ABL1基因的染色体易位t(1;9)(q24;q34) 。
Leuk Res. 2011 Sep;35(9):e149-50. doi: 10.1016/j.leukres.2011.05.008.
8
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.针对化疗耐药的 B 系急性淋巴细胞白血病患者微小残留病灶的 T 细胞结合抗体blinatumomab 的靶向治疗可带来高缓解率和延长无白血病生存。
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ABL1 fusion genes in hematological malignancies: a review.血液恶性肿瘤中的 ABL1 融合基因：综述。
Eur J Haematol. 2011 May;86(5):361-71. doi: 10.1111/j.1600-0609.2011.01586.x. Epub 2011 Mar 23.
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The t(1;9)(p34;q34) fusing ABL1 with SFPQ, a pre-mRNA processing gene, is recurrent in acute lymphoblastic leukemias.使ABL1与一种前体mRNA加工基因SFPQ融合的t(1;9)(p34;q34)在急性淋巴细胞白血病中反复出现。
Leuk Res. 2011 Jul;35(7):e114-7. doi: 10.1016/j.leukres.2011.02.011. Epub 2011 Mar 9.