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玻璃体内注射地塞米松植入剂（Ozurdex）治疗色素性视网膜炎继发的难治性黄斑水肿。

Intravitreal Dexamethasone Implant (Ozurdex) for Refractory Macular Edema Secondary to Retinitis Pigmentosa.

作者信息

Örnek Nurgül, Örnek Kemal, Erbahçeci İnci Elif

机构信息

Kırıkkale University Faculty of Medicine, Department of Ophthalmology, Kırıkkale, Turkey.

出版信息

Turk J Ophthalmol. 2016 Aug;46(4):179-181. doi: 10.4274/tjo.60437. Epub 2016 Aug 15.

DOI:10.4274/tjo.60437
PMID:28058154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5200824/
Abstract

Macular edema (ME) in retinitis pigmentosa (RP) often impairs central vision dramatically. A 41-year-old woman diagnosed with RP was referred to our outpatient clinic due to severe visual deterioration in both eyes. The patient was treated with topical carbonic anhydrase inhibitors, topical corticosteroids and intravitreal triamcinolone acetonide injections, but her ME recurred. Intravitreal 0.7 mg dexamethasone implant (Ozurdex, Allergan) was administered into both eyes without complications. On the fourth day after both injections, visual acuity improved and ME almost totally resolved. No recurrence was observed at follow-up six months later.

摘要

视网膜色素变性（RP）中的黄斑水肿（ME）常常会严重损害中心视力。一名41岁被诊断为RP的女性因双眼严重视力下降被转诊至我们的门诊。该患者接受了局部碳酸酐酶抑制剂、局部皮质类固醇和玻璃体内注射曲安奈德治疗，但她的ME复发了。双眼均注射了0.7毫克玻璃体内地塞米松植入剂（Ozurdex，爱尔康公司），未出现并发症。两次注射后的第四天，视力提高，ME几乎完全消退。六个月后的随访中未观察到复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/b64620a958ab/TJO-46-179-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/d33987880a13/TJO-46-179-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/c0026ecb4af5/TJO-46-179-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/54dd6e48e451/TJO-46-179-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/dc80e4100f94/TJO-46-179-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/437e425f08b0/TJO-46-179-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/b64620a958ab/TJO-46-179-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/d33987880a13/TJO-46-179-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/c0026ecb4af5/TJO-46-179-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/54dd6e48e451/TJO-46-179-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/dc80e4100f94/TJO-46-179-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/437e425f08b0/TJO-46-179-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89d9/5200824/b64620a958ab/TJO-46-179-g6.jpg

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本文引用的文献

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The effect of an intravitreal dexamethasone implant for cystoid macular edema in retinitis pigmentosa: a case report and literature review.玻璃体内注射地塞米松植入物治疗色素性视网膜炎黄斑囊样水肿的疗效：病例报告及文献综述
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