Ozer Mehmet Nuri, Uzunlulu Mehmet, Oguz Aytekin, Kostek Osman, Akyer Erdal, Takir Mumtaz
Department of Internal Medicine, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.
Department of Internal Medicine and Division of Endocrinology, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.
North Clin Istanb. 2015 Apr 24;2(1):41-47. doi: 10.14744/nci.2015.41713. eCollection 2015.
The aim of this study was to evaluate the sociodemographic and clinical chracteristics of patients hospitalized with aspiration pneumonia in internal medicine clinics, and to determine the incidence and parameters of mortality among these patients.
Patients over the age of 18 years who were hospitalized in clinics of internal medicine between January 1, 2010 and January 1, 2013 (115 male, 89 female; mean age: 77±13 years; patients aged 65 years and over, 88.2%; average duration of hospitalization, 11±9 days) were evaluated retrospectively and consecutively. The incidence of mortality, nutritional status at admission, comorbidity frequency, haematological and biochemical data and their relationship with mortality were evaluated.
At admission, 85% of the patients were fed through oral route, while 15% of them were fed through PEG. There was no relation between nutritional status of the patients (oral, nasogastric tube or PEG) at admission, and development of aspiration pneumonia. Commonly seen comorbidities were dementia (49%), hypertension (43%), cerebrovascular accident (42%), and diabetes mellitus (31%) respectively. The mortality rate was 24.5% (in first three days, 56%). A correlation was found between mortality and increase in neutrophil/lymphocyte ratio (NLR) and increased uric acid rate (for both p<0.05).
In this study, the mortality rates among patients diagnosed with aspiration pneumonia was found to be increased. The high number of geriatric patients and comorbidities might have played a role in this situation. Neutrophil/lymphocyte ratio (NLR) and uric acid levels in patients with aspiration pneumonia might be evaluated as factors related to mortality.
本研究旨在评估在内科诊所因吸入性肺炎住院患者的社会人口学和临床特征，并确定这些患者的死亡率及相关参数。
对2010年1月1日至2013年1月1日期间在内科诊所住院的18岁以上患者（115例男性，89例女性；平均年龄：77±13岁；65岁及以上患者占88.2%；平均住院时间11±9天）进行回顾性连续评估。评估死亡率、入院时营养状况、合并症发生率、血液学和生化数据及其与死亡率的关系。
入院时，85%的患者通过口服途径进食，15%通过经皮内镜下胃造口术（PEG）进食。患者入院时的营养状况（口服、鼻胃管或PEG）与吸入性肺炎的发生无关。常见的合并症分别为痴呆（49%）、高血压（43%）、脑血管意外（42%）和糖尿病（31%）。死亡率为24.5%（前三天为56%）。发现死亡率与中性粒细胞/淋巴细胞比值（NLR）升高和尿酸率升高相关（两者p<0.05）。
本研究发现，诊断为吸入性肺炎的患者死亡率有所增加。老年患者数量众多及合并症可能在这种情况中起了作用。吸入性肺炎患者的中性粒细胞/淋巴细胞比值（NLR）和尿酸水平可作为与死亡率相关的因素进行评估。
