Dreber H, Reynisdottir S, Angelin B, Tynelius P, Rasmussen F, Hemmingsson E
Obesity Centre, Karolinska University Hospital, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Clin Obes. 2017 Feb;7(1):1-10. doi: 10.1111/cob.12170. Epub 2017 Jan 6.
Young adults (18-25) with severe obesity constitute a challenging patient group, and there is limited evidence about their mental health status compared to population controls. Mental distress in treatment seeking young adults with severe obesity (n = 121, mean body mass index [BMI] = 39.8 kg m ) was compared with matched (1:3 for age, gender and socioeconomic status) population controls of normal weight (n = 363, mean BMI = 22.4 kg m ), as well as unmatched population controls with class I obesity (n = 105, mean BMI = 32.1 kg m ) or severe obesity (n = 41, mean BMI = 39.7 kg m ). Mental distress was measured by the General Health Questionnaire-12 (GHQ-12), and we quantified physician-diagnosed depression, present anxiety and suicide attempts. Poisson regression and linear regression analysis were used for analysing differences in mental distress between groups. Treatment seekers experienced more mental distress than normal weight controls as measured by continuous (adjusted mean: 3.9 vs. 2.2 points, P <0.001) and categorical (cut-off for mental distress ≥3 points, RR: 1.76, P <0.001) GHQ-12 scores, depression (RR: 2.18, P < 0.001), anxiety (RR: 1.97, P < 0.001) and suicide attempts (RR: 2.04; P = 0.034). Treatment seekers also experienced more mental distress as measured by continuous GHQ-12 than controls with class I obesity (adjusted mean: 2.3 points) or severe obesity (adjusted mean: 2.1; both, P < 0.001). Young adult treatment seekers with severe obesity constitute a risk group for mental distress compared to population controls of different BMI levels.
患有严重肥胖症的年轻成年人(18 - 25岁)是一个具有挑战性的患者群体,与一般人群对照组相比,关于他们心理健康状况的证据有限。将寻求治疗的患有严重肥胖症的年轻成年人(n = 121,平均体重指数[BMI] = 39.8 kg/m²)与匹配的(年龄、性别和社会经济地位1:3)正常体重的一般人群对照组(n = 363,平均BMI = 22.4 kg/m²),以及不匹配的I级肥胖(n = 105,平均BMI = 32.1 kg/m²)或严重肥胖(n = 41,平均BMI = 39.7 kg/m²)的一般人群对照组进行比较。通过一般健康问卷-12(GHQ-12)测量心理困扰,我们对医生诊断的抑郁症、当前焦虑症和自杀企图进行了量化。采用泊松回归和线性回归分析来分析各组之间心理困扰的差异。如通过连续(调整后均值:3.9对2.2分,P <0.001)和分类(心理困扰临界值≥3分,RR:1.76,P <0.001)的GHQ-12评分、抑郁症(RR:2.18,P <0.001)、焦虑症(RR:1.97,P <0.001)和自杀企图(RR:2.04;P = 0.034)所测量的那样,寻求治疗者比正常体重对照组经历更多的心理困扰。与连续GHQ-12测量的I级肥胖对照组(调整后均值:2.3分)或严重肥胖对照组(调整后均值:2.1分;两者,P <0.001)相比,寻求治疗者也经历更多的心理困扰。与不同BMI水平的一般人群对照组相比,患有严重肥胖症的年轻成年寻求治疗者构成心理困扰的风险群体。