在一名死于脊索瘤的儿童中使用3T背景抑制扩散加权成像（DWIBS）进行全身MRI虚拟尸检
Whole-Body MRI Virtual Autopsy Using Diffusion-weighted Imaging With Background Suppression (DWIBS) at 3 T in a Child Succumbing to Chordoma.
作者信息
Andronikou Savvas, Kemp Marnie L, Meiring Michelle
机构信息
*Department of Paediatric Radiology, Bristol Royal Hospital for Children, The University of Bristol, Bristol, UK †Department of Diagnostic Radiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg ‡Department of Paediatrics and Child Health, Red Cross Children's Hospital, The University of Cape Town, Cape Town, South Africa.
出版信息
J Pediatr Hematol Oncol. 2017 Mar;39(2):133-136. doi: 10.1097/MPH.0000000000000759.
BACKGROUND
We report the use of diffusion-weighted imaging with background suppression (DWIBS) in pediatric virtual magnetic resonance imaging (MRI) autopsy of a child who succumbed to chordoma.
CASE DESCRIPTION
A 10-year-old girl who succumbed to relapse of a chordoma underwent whole-body virtual MRI autopsy 12 hours postmortem with short Tau inversion recovery (STIR) and DWIBS on 3 T, which demonstrated the primary mass, local and cardiac invasion, and metastatic disease to the thorax, abdomen, head/neck, and musculoskeletal system.
CONCLUSIONS
Postmortem virtual MRI autopsy including DWIBS successfully demonstrated the transthoracic spread of chordoma and invasion of the heart, resulting in blood-borne metastases. Motion and respiratory artifact were not factors during virtual autopsy using DWIBS on 3 T, making ideal use of this technology.
背景
我们报告了在一名死于脊索瘤的儿童的儿科虚拟磁共振成像（MRI）尸检中使用背景抑制扩散加权成像（DWIBS）的情况。
病例描述
一名10岁女孩因脊索瘤复发死亡，死后12小时在3T磁共振成像仪上采用短反转时间反转恢复序列（STIR）和背景抑制扩散加权成像（DWIBS）进行了全身虚拟MRI尸检，显示了原发肿块、局部及心脏侵犯以及胸部、腹部、头颈部和肌肉骨骼系统的转移病灶。
结论
包括背景抑制扩散加权成像（DWIBS）在内的死后虚拟MRI尸检成功显示了脊索瘤的经胸扩散及心脏侵犯，导致血行转移。在3T磁共振成像仪上使用背景抑制扩散加权成像（DWIBS）进行虚拟尸检时，运动和呼吸伪影不是影响因素，该技术得到了理想应用。
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