黑素细胞瘤还是乳头旁黑色素瘤？
MELANOCYTOMA OR JUXTAPAPILLARY MELANOMA?
作者信息
Baartman Brandon J, Ahmad Baseer, Srivastava Sunil, Jones Stephen, Singh Arun D
机构信息
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
Department of Vitreoretinal Diseases and Surgery, University Hospitals Eye Institute, Case Western Reserve School of Medicine, Cleveland, Ohio.
出版信息
Retin Cases Brief Rep. 2019;13(1):15-17. doi: 10.1097/ICB.0000000000000520.
PURPOSE
To report the case of a melanocytoma of the optic disc leading to severe vision loss, raising concern for possible malignant transformation and optic nerve infiltration.
METHODS
Case report.
RESULTS
A 36-year-old Arabic woman presented to an outside facility with severe vision loss and a clinical picture concerning for optic neuritis with central retinal vein occlusion. On referral to the authors' institution 1 month after initial presentation, the vision of the patient was no light perception in the affected eye, and examination revealed the presence of a pigmented lesion adjacent to the nerve. Although standard 3-T magnetic resonance imaging orbits suggested 15 mm of optic nerve involvement, ultrahigh resolution 7-T magnetic resonance imaging was able to detect only 2 mm of optic nerve involvement.
CONCLUSION
Melanocytoma of the optic disc is most often benign and causes few visual symptoms. However, in rare cases it can lead to severe vision loss and raise concern for malignant transformation. A 7-T magnetic resonance imaging provides higher resolution optic nerve images.
目的
报告一例导致严重视力丧失的视盘黑色素细胞瘤病例，引发对可能的恶性转化和视神经浸润的关注。
方法
病例报告。
结果
一名36岁的阿拉伯女性因严重视力丧失就诊于外部机构，临床表现疑似视神经炎合并视网膜中央静脉阻塞。初次就诊1个月后转诊至作者所在机构时，患眼视力无光感，检查发现神经旁有色素沉着病变。尽管标准的3T眼眶磁共振成像显示视神经受累长度为15毫米，但超高分辨率的7T磁共振成像仅能检测到2毫米的视神经受累。
结论
视盘黑色素细胞瘤大多为良性，很少引起视觉症状。然而，在罕见情况下，它可导致严重视力丧失并引发对恶性转化的担忧。7T磁共振成像可提供更高分辨率的视神经图像。
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