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单麻醉与分期双侧全髋关节置换术:一项匹配队列研究。

Single-Anesthetic Versus Staged Bilateral Total Hip Arthroplasty: A Matched Cohort Study.

作者信息

Houdek Matthew T, Wyles Cody C, Watts Chad D, Wagner Eric R, Sierra Rafael J, Trousdale Robert T, Taunton Michael J

机构信息

1Mayo Clinic, Rochester, Minnesota.

出版信息

J Bone Joint Surg Am. 2017 Jan 4;99(1):48-54. doi: 10.2106/JBJS.15.01223.

Abstract

BACKGROUND

There is debate regarding the role of single-anesthetic versus staged bilateral total hip arthroplasty (THA) for patients with end-stage bilateral osteoarthritis. Studies have shown that single-anesthetic bilateral THA is associated with systemic complications, but there are limited data comparing patient outcomes in a matched setting of bilateral THA.

METHODS

We identified 94 patients (188 hips) who underwent single-anesthetic bilateral THA. Fifty-seven percent of the patients were male. Patients had a mean age of 52.2 years and body mass index of 27.1 kg/m. They were matched 1:1 on the basis of sex, age (±1 year), and year of surgery (±3 years) to a cohort of patients undergoing staged bilateral THA. In the staged group, there was <1 year between procedures (range, 5 days to 10 months). Mean follow-up was 4 years for each group.

RESULTS

Patients in the single-anesthetic group experienced shorter total operating room time and length of stay. There was no difference (hazard ratio [HR] = 0.73, p = 0.50) in the overall revision-free survival in patients undergoing single-anesthetic or staged bilateral THA. The risks of reoperation (HR = 0.69, p = 0.40), complications (HR = 0.83, p = 0.48), and mortality (HR = 0.47, p = 0.10) were similar. Single-anesthetic bilateral THA reduced the total cost of care (by 27%, p = 0.0001).

CONCLUSIONS

In this matched cohort analysis, single-anesthetic bilateral THA was not associated with an increased risk of revision, reoperation, or postoperative complications, while decreasing cost. In our experience, single-anesthetic bilateral THA is a safe procedure that, for certain patients, offers an excellent means to deal with bilateral hip osteoarthritis.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

对于终末期双侧骨关节炎患者,单麻醉一次完成双侧全髋关节置换术(THA)与分期双侧THA的作用存在争议。研究表明,单麻醉一次完成双侧THA与全身并发症相关,但在双侧THA匹配情况下比较患者预后的数据有限。

方法

我们纳入了94例行单麻醉一次完成双侧THA的患者(188髋)。57%的患者为男性。患者的平均年龄为52.2岁,体重指数为27.1kg/m²。根据性别、年龄(±1岁)和手术年份(±3年),将他们与分期双侧THA患者队列进行1:1匹配。在分期组中,两次手术之间间隔<1年(范围为5天至10个月)。每组的平均随访时间为4年。

结果

单麻醉组患者的总手术室时间和住院时间较短。接受单麻醉或分期双侧THA的患者在总体无翻修生存率方面无差异(风险比[HR]=0.73,p=0.50)。再次手术风险(HR=0.69,p=0.40)、并发症风险(HR=0.83,p=0.48)和死亡率(HR=0.47,p=0.10)相似。单麻醉一次完成双侧THA降低了护理总成本(降低27%,p=0.0001)。

结论

在这项匹配队列分析中,单麻醉一次完成双侧THA与翻修、再次手术或术后并发症风险增加无关,同时降低了成本。根据我们的经验,单麻醉一次完成双侧THA是一种安全的手术方法,对于某些患者来说,是治疗双侧髋关节骨关节炎的极佳手段。

证据级别

治疗性三级证据。有关证据级别的完整描述,请参阅作者指南。

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