Qi X D
Cancer Institute, China University of Medical Sciences, Shenyang.
Zhonghua Zhong Liu Za Zhi. 1989 Mar;11(2):136-8.
Gastroscopic mucosal biopsies and carbon ink injection marking were performed in 31 patients with gastric cancer before operation. The resection line of gastric wall was determined during operation according to the marked points. The method, dose, site, and opportunity of ink injection were studied. The results were: 1. None of these 31 patients had positive biopsies from cancer free areas. None of the resected specimens showed deep cancer infiltration beyond the site of carbon ink injection. This method is significant in recognizing the extent of intramucosal cancer infiltration; 2. None of the 31 patients marked by ink injection had residual cancer on the resected line whereas 8-10% of those unmarked had a positive margin. This result indicates that this method is significant in avoiding residual cancer on the resection line; and 3. Before surgery, the home-made carbon ink was satisfactory. The optimum dose for an ideal ink point was 0.05-0.1 ml/point which would give a marking of 0.5-1.5 cm in diameter on the serosa. The ink point was clearly shown on the anterior wall but less satisfactorily on the lesser curvature of the stomach. Injection performed as early as the fifth week before operation was valid.
对31例胃癌患者术前进行了胃镜黏膜活检及碳素墨水注射标记。术中根据标记点确定胃壁的切除线。对墨水注射的方法、剂量、部位及时机进行了研究。结果显示：1. 这31例患者中，无1例在癌旁无癌区域活检呈阳性。切除标本中无1例显示癌浸润深度超过碳素墨水注射部位。该方法对识别黏膜内癌浸润范围具有重要意义；2. 31例经墨水注射标记的患者，切除线上均无残留癌，而未标记的患者中8 - 10%切缘阳性。这一结果表明该方法对避免切除线上残留癌具有重要意义；3. 术前，自制的碳素墨水效果良好。理想墨点的最佳剂量为0.05 - 0.1 ml/点，在浆膜上可形成直径0.5 - 1.5 cm的标记。墨点在前壁显示清晰，但在胃小弯处显示欠佳。术前第5周尽早进行注射有效。
