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孕34周后使用产前糖皮质激素时我们应谨慎行事。

We Should Proceed With Caution When It Comes to Antenatal Corticosteroids After 34 Weeks.

作者信息

Nowik Christina M, Davies Gregory A L, Smith Graeme N

机构信息

Department of Obstetrics and Gynaecology, Kingston General Hospital, Kingston ON.

出版信息

J Obstet Gynaecol Can. 2017 Jan;39(1):49-51. doi: 10.1016/j.jogc.2016.05.011. Epub 2016 Dec 10.

DOI:10.1016/j.jogc.2016.05.011
PMID:28062023
Abstract

The Society for Maternal-Fetal Medicine recently released a statement supporting the use of antenatal corticosteroids for women at high risk of late preterm birth. This followed a trend of increasing use of antenatal corticosteroids after 34 weeks' gestation, based on evidence for decreased respiratory morbidity. The absolute benefits, however, are relatively small. We should balance this against the possible long-term harms of corticosteroids after 34 weeks before expanding the indications for their antenatal use.

摘要

母胎医学会最近发布了一份声明,支持对晚期早产高危女性使用产前糖皮质激素。这是基于34周妊娠后呼吸疾病发病率降低的证据,使用产前糖皮质激素的趋势不断增加之后的举措。然而,绝对益处相对较小。在扩大其产前使用指征之前,我们应权衡这一点与34周后糖皮质激素可能带来的长期危害。

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2
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引用本文的文献

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A comparison of short- and long-term prognoses between cases with and without antenatal corticosteroid administration in late preterm delivery: a nationwide population-based study.晚期早产中使用与未使用产前皮质类固醇病例的短期和长期预后比较:一项基于全国人群的研究。
BMC Pregnancy Childbirth. 2025 Feb 12;25(1):148. doi: 10.1186/s12884-024-06851-y.
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Antenatal corticosteroid administration and attention-deficit/hyperactivity disorder in childhood: a regression discontinuity study.产前皮质类固醇给药与儿童注意缺陷/多动障碍:回归不连续性研究。
CMAJ. 2022 Feb 22;194(7):E235-E241. doi: 10.1503/cmaj.211491.
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Timing of antenatal corticosteroids in relation to clinical indication.
产前皮质类固醇的时机与临床指征的关系。
Arch Gynecol Obstet. 2022 Oct;306(4):997-1005. doi: 10.1007/s00404-021-06362-7. Epub 2022 Jan 18.
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Antenatal corticosteroid administration and early school age child development: A regression discontinuity study in British Columbia, Canada.产前皮质类固醇给药与儿童早期学校年龄发育:加拿大不列颠哥伦比亚的回归不连续研究。
PLoS Med. 2020 Dec 7;17(12):e1003435. doi: 10.1371/journal.pmed.1003435. eCollection 2020 Dec.