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产前使用糖皮质激素促进胎儿成熟的指南。

Guideline for the use of antenatal corticosteroids for fetal maturation.

作者信息

Miracle Xavier, Di Renzo Gian Carlo, Stark Ann, Fanaroff Avroy, Carbonell-Estrany Xavier, Saling Erich

机构信息

Neonatology Service, Hospital Clinic, Institut Clinic de Ginecologia, Obstetricia I Neonatologia, Universitat de Barcelona, Barcelona, Spain.

出版信息

J Perinat Med. 2008;36(3):191-6. doi: 10.1515/JPM.2008.032.

Abstract

The aim is to present a document, which is based on current evidence and serves as a guideline for use in clinical practice. The following questions are addressed: Is the use of antenatal corticosteroids (ACS) an effective therapy? Who are the candidates for antenatal corticosteroid therapy? Is there benefit after 34 weeks' gestation? When is the optimal time to treat? Which are the optimal steroids; what is the ideal dose and route of administration? Are there any contraindications to the administration of ACS? Are antenatal corticosteroids indicated in women with premature rupture of membranes (PROM)? Is the use of ACS recommended in pregnancies complicated by maternal diabetes mellitus? Should the treatment with corticosteroids be repeated?

摘要

目的是提供一份基于当前证据、可作为临床实践使用指南的文件。探讨了以下问题:产前使用糖皮质激素(ACS)是否为有效疗法?哪些人是产前糖皮质激素治疗的适用对象?妊娠34周后是否有益?最佳治疗时间是什么时候?哪种是最佳糖皮质激素;理想剂量和给药途径是什么?使用ACS有无禁忌证?胎膜早破(PROM)的女性是否需要使用产前糖皮质激素?患有妊娠合并糖尿病的孕妇是否推荐使用ACS?糖皮质激素治疗是否应重复进行?

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