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Pharmacokinetics of Pomalidomide in a Patient Receiving Hemodialysis Using a High-Cutoff Filter.

作者信息

Dao Kim, Chtioui Haithem, Lu Yimin, Peer Cody J, Figg William D, Pruijm Menno, Buclin Thierry, Kissling Sébastien

机构信息

Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

出版信息

Am J Kidney Dis. 2017 Apr;69(4):553-554. doi: 10.1053/j.ajkd.2016.10.026. Epub 2017 Jan 4.

DOI:10.1053/j.ajkd.2016.10.026
PMID:28063733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6667183/
Abstract
摘要

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An Open-Label, Phase 1 Study to Assess the Effects of Hepatic Impairment on Pomalidomide Pharmacokinetics.一项评估肝损伤对泊马度胺药代动力学影响的开放标签、1 期研究。
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本文引用的文献

1
Population pharmacokinetics of pomalidomide.泊马度胺的群体药代动力学。
J Clin Pharmacol. 2015 May;55(5):563-72. doi: 10.1002/jcph.455. Epub 2015 Feb 4.
2
Pharmacokinetic considerations in chronic kidney disease and patients requiring dialysis.慢性肾脏病及需要透析的患者的药代动力学考量
Expert Opin Drug Metab Toxicol. 2014 Aug;10(8):1131-43. doi: 10.1517/17425255.2014.931371. Epub 2014 Jun 24.
3
A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses.一种用于药代动力学分析的灵敏且稳健的高效液相色谱（HPLC）荧光检测法，用于定量测定人血浆中的泊马度胺。
J Pharm Biomed Anal. 2014 Apr;92:63-8. doi: 10.1016/j.jpba.2014.01.001. Epub 2014 Jan 9.
4
Pharmacokinetic evaluation of pomalidomide for the treatment of myeloma.泊马度胺用于骨髓瘤治疗的药代动力学评价。
Expert Opin Drug Metab Toxicol. 2013 Nov;9(11):1517-27. doi: 10.1517/17425255.2013.827169. Epub 2013 Aug 21.
5
Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration.口服[14C]泊马度胺后在人体内的吸收、代谢和排泄。
Cancer Chemother Pharmacol. 2013 Feb;71(2):489-501. doi: 10.1007/s00280-012-2040-6. Epub 2012 Dec 1.