Teculescu D B, Aubry C, Pham Q T, Locuty J, Deschamps J P, Manciaux M
INSERM Unité 115, Vandoeuvre les Nancy, France.
Eur Respir J. 1989 Sep;2(8):733-5.
Ventilatory function (forced vital capacity, forced expiratory volume in one second, forced expiratory flows), static lung volumes, phase III slope and closing volume (single-breath nitrogen washout test) were measured in 499 children and adolescents aged 10-16 yrs from a general population sample in North-East France. A history of whooping cough was given by 44 children (22 of each sex); their results were compared to those of the 455 children (215 girls) with a negative history. The only difference between the two groups was a minimal increase in the residual volume/total lung capacity ratio in cases (19.2 +/- 3.1 vs 18.0 +/- 2.9%). We conclude that uncomplicated whooping cough in early childhood did not lead to significant pulmonary function abnormality in this population of children born after 1967.
对来自法国东北部普通人群样本的499名10至16岁儿童及青少年进行了通气功能（用力肺活量、一秒用力呼气量、用力呼气流量）、静态肺容量、第三相斜率及闭合气量（单次呼吸氮洗脱试验）的测量。44名儿童（男女各22名）有百日咳病史；将他们的结果与455名（215名女孩）无百日咳病史儿童的结果进行比较。两组之间唯一的差异是病例组的残气量/肺总量比值略有增加（19.2±3.1%对18.0±2.9%）。我们得出结论，1967年以后出生的这群儿童中，幼儿期患无并发症的百日咳并未导致显著的肺功能异常。
