迭代模型重建可减少冠状动脉CT血管造影中的钙化斑块体积。
Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography.
作者信息
Károlyi Mihály, Szilveszter Bálint, Kolossváry Márton, Takx Richard A P, Celeng Csilla, Bartykowszki Andrea, Jermendy Ádám L, Panajotu Alexisz, Karády Júlia, Raaijmakers Rolf, Giepmans Walter, Merkely Béla, Maurovich-Horvat Pál
机构信息
MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68. Varosmajor st, 1122, Budapest, Hungary.
Department of Radiology, University Medical Center Utrecht, 100 Heidelberglaan, 3584, CX Utrecht, The Netherlands.
出版信息
Eur J Radiol. 2017 Feb;87:83-89. doi: 10.1016/j.ejrad.2016.12.012. Epub 2016 Dec 14.
OBJECTIVE
To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA).
METHODS
Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software.
RESULTS
Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p<0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5-59.9], 20.3 [16.2-25.9] and 14.0 [11.2-17.7], respectively, all p<0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3-168.4], 138.7 [90.6-191.7], 147.0 [100.7-183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1-144.6], 110.2 [63.8-166.6], 115.9 [81.7-164.2], respectively, p<0.05 all). High-attenuation non-calcified volumes (90-129 HU) yielded similar values with FBP and HIR (p=0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30-89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p=0.22 and p=0.67, respectively).
CONCLUSIONS
IMR improves image quality of coronary CTA and decreases calcified plaque volumes.
目的
在冠状动脉计算机断层扫描血管造影（CTA）中，评估迭代模型重建（IMR）与滤波反投影重建（FBP）及混合迭代重建（HIR）相比，对钙化斑块定量分析的影响。
方法
对52例行256层CTA检查患者的原始图像数据分别采用IMR、HIR和FBP进行重建。我们评估了定性、定量图像质量参数，并使用自动化软件对钙化及部分钙化斑块体积进行定量分析。
结果
与FBP相比，HIR的整体定性图像质量显著改善，而IMR使其进一步提高（均p<0.01）。与HIR和FBP相比，IMR提高了对比噪声比（分别为51.0[43.5 - 59.9]、20.3[16.2 - 25.9]和14.0[11.2 - 17.7]，均p<0.01）。IMR的总体斑块体积最低，FBP最高（分别为121.7[79.3 - 168.4]、138.7[90.6 - 191.7]、147.0[100.7 - 183.6]）。同样，与HIR和FBP相比，IMR使钙化体积（>130 HU）减少（分别为105.9[62.1 - 144.6]、110.2[63.8 - 166.6]、115.9[81.7 - 164.2]，均p<0.05）。高衰减非钙化体积（90 - 129 HU）在FBP和HIR中的值相似（p = 0.81），但IMR中的值较低（均p < 0.05）。中等衰减（30 - 89 HU）和低衰减（<30 HU）非钙化体积无显著差异（分别为p = 0.22和p = 0.67）。
结论
IMR改善了冠状动脉CTA的图像质量并减少了钙化斑块体积。
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