先天性心脏病婴儿中基于模型的迭代重建CT血管造影的图像质量：与滤波反投影和混合迭代重建的比较
Image quality of ct angiography using model-based iterative reconstruction in infants with congenital heart disease: Comparison with filtered back projection and hybrid iterative reconstruction.
作者信息
Jia Qianjun, Zhuang Jian, Jiang Jun, Li Jiahua, Huang Meiping, Liang Changhong
机构信息
Southern Medical University, Guangzhou, Guangdong, China; Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China; Department of Catheterization Lab, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
出版信息
Eur J Radiol. 2017 Jan;86:190-197. doi: 10.1016/j.ejrad.2016.10.017. Epub 2016 Oct 17.
PURPOSE
To compare the image quality, rate of coronary artery visualization and diagnostic accuracy of 256-slice multi-detector computed tomography angiography (CTA) with prospective electrocardiographic (ECG) triggering at a tube voltage of 80kVp between 3 reconstruction algorithms (filtered back projection (FBP), hybrid iterative reconstruction (iDose) and iterative model reconstruction (IMR)) in infants with congenital heart disease (CHD).
METHODS
Fifty-one infants with CHD who underwent cardiac CTA in our institution between December 2014 and March 2015 were included. The effective radiation doses were calculated. Imaging data were reconstructed using the FBP, iDose and IMR algorithms. Parameters of objective image quality (noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR)); subjective image quality (overall image quality, image noise and margin sharpness); coronary artery visibility; and diagnostic accuracy for the three algorithms were measured and compared.
RESULTS
The mean effective radiation dose was 0.61±0.32 mSv. Compared to FBP and iDose, IMR yielded significantly lower noise (P<0.01), higher SNR and CNR values (P<0.01), and a greater subjective image quality score (P<0.01). The total number of coronary segments visualized was significantly higher for both iDose and IMR than for FBP (P=0.002 and P=0.025, respectively), but there was no significant difference in this parameter between iDose and IMR (P=0.397). There was no significant difference in the diagnostic accuracy between the FBP, iDose and IMR algorithms (χ=0.343, P=0.842).
CONCLUSIONS
For infants with CHD undergoing cardiac CTA, the IMR reconstruction algorithm provided significantly increased objective and subjective image quality compared with the FBP and iDose algorithms. However, IMR did not improve the diagnostic accuracy or coronary artery visualization compared with iDose.
目的
比较256层多探测器计算机断层扫描血管造影（CTA）在80kVp管电压下采用前瞻性心电图（ECG）触发时，三种重建算法（滤波反投影（FBP）、混合迭代重建（iDose）和迭代模型重建（IMR））对先天性心脏病（CHD）婴儿的图像质量、冠状动脉显影率及诊断准确性。
方法
纳入2014年12月至2015年3月在我院接受心脏CTA检查的51例CHD婴儿。计算有效辐射剂量。使用FBP、iDose和IMR算法重建影像数据。测量并比较三种算法的客观图像质量参数（噪声、信噪比（SNR）和对比噪声比（CNR））、主观图像质量（整体图像质量、图像噪声和边缘清晰度）、冠状动脉可视性及诊断准确性。
结果
平均有效辐射剂量为0.61±0.32 mSv。与FBP和iDose相比，IMR产生的噪声显著更低（P<0.01），SNR和CNR值更高（P<0.01），主观图像质量评分更高（P<0.01）。iDose和IMR显示的冠状动脉节段总数均显著高于FBP（分别为P=0.002和P=0.025），但iDose和IMR之间此参数无显著差异（P=0.397）。FBP、iDose和IMR算法之间的诊断准确性无显著差异（χ=0.343，P=0.842）。
结论
对于接受心脏CTA检查的CHD婴儿，与FBP和iDose算法相比，IMR重建算法显著提高了客观和主观图像质量。然而，与iDose相比，IMR并未提高诊断准确性或冠状动脉显影效果。
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