Surkova L A, Tiurina I V
Farmakol Toksikol. 1989 Jul-Aug;52(4):93-5.
An animal model of addiction is described. The albino rats learned to come into the right arm of the Y-type maze where they received intraperitoneal injections of morphine in a dose of 5 mg/kg or distilled water (control group). It was found that morphine-dependent rats much more frequently visited the right arm. Thus it is possible to estimate quantitatively the positive reinforcing effect of morphine.
描述了一种成瘾动物模型。白化大鼠学会进入Y型迷宫的右臂，在那里它们接受腹腔注射5毫克/千克剂量的吗啡或蒸馏水（对照组）。发现对吗啡产生依赖的大鼠更频繁地进入右臂。因此，有可能定量评估吗啡的正强化作用。
