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[红细胞计数增加对大鼠脑微血管快速血流波动的影响]

[The effect of an increased erythrocyte count on rapid blood flow fluctuations in the microvessels of the rat brain].

作者信息

Kisliakov Iu Ia, Levkovich Iu I, Shumilova T E, Vershinina E A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Jun;75(6):777-85.

PMID:2806644
Abstract

Polycythemia was achieved by means of substitution of the rat own blood (2 ml) with the same volume of washed out erythrocytes, the hematocrit increasing from 44 to 54%. Excessive erythrocytes altered the structure of the erythrocyte flow, its diameter being 3-13 mu. The rate of occurrence of the plasma lumens decreased. The hematocrit increase, however, did not affect the amplitude and period of the oscillations. The character of distribution of periodic components of the fluctuations of the blood flow linear velocity did not change either in the vessels under study. The data obtained suggests that the erythrocytes do not affect the occurrence of the blood flow oscillations in the microcirculation system. The main part in their formation seems to be played by the leucocytes differing by their rheological features from erythrocytes.

摘要

通过用相同体积的洗出红细胞替代大鼠自身血液(2毫升)来实现红细胞增多症,血细胞比容从44%增加到54%。过多的红细胞改变了红细胞流的结构,其直径为3 - 13微米。血浆腔出现的速率降低。然而,血细胞比容的增加并未影响振荡的幅度和周期。在所研究的血管中,血流线性速度波动的周期性成分的分布特征也没有改变。所获得的数据表明,红细胞不会影响微循环系统中血流振荡的发生。在其形成过程中起主要作用的似乎是白细胞,其流变学特征与红细胞不同。

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