Vervliet J, De Cleyn K, Renier M, Janssens P, Buytaert P, Gerris J, Delbeke L
Department of Obstetrics and Gynecology, University Hospital Antwerp, Edegem, Belgium.
Eur J Obstet Gynecol Reprod Biol. 1989 Oct;33(1):61-9. doi: 10.1016/0028-2243(89)90079-8.
The course of gestation and the outcome of fifteen triplet and six quadruplet pregnancies are reviewed. Twenty pregnancies followed induction of ovulation and only one was spontaneous. Bed rest, the use of beta-mimetics and betamethasone, and prolonged hospitalisation were part of the management. Elective cervical suture was not used. The most frequent antenatal complications were preterm labor, preterm rupture of membranes and pregnancy-induced hypertension. The median gestational age was 33.5 weeks in the triplets and 32 weeks in the quadruplets. The overall perinatal and neonatal mortality was 4.9%. The neonatal complications resulted from prematurity and sepsis.
本文回顾了15例三胎妊娠和6例四胎妊娠的妊娠过程及结局。其中20例为促排卵后妊娠，仅1例为自然受孕。卧床休息、使用β-拟交感神经药和倍他米松以及延长住院时间是治疗措施的一部分。未采用选择性宫颈环扎术。最常见的产前并发症为早产、胎膜早破和妊娠高血压。三胎妊娠的中位孕周为33.5周，四胎妊娠为32周。围产期和新生儿的总体死亡率为4.9%。新生儿并发症由早产和败血症引起。
