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BEAM conditioning is well-tolerated and yields similar survival in obese and non-obese patients with lymphoma: no requirement for weight-based dose modifications.

作者信息

Fair C, Shanley R, Rogosheske J, Lazaryan A, McClune B, Brunstein C G, Bachanova V

机构信息

Blood and Marrow Transplantation Program, University of Minnesota Medical Center, Minneapolis, MN, USA.

出版信息

Bone Marrow Transplant. 2017 Mar;52(3):491-493. doi: 10.1038/bmt.2016.316. Epub 2017 Jan 9.

DOI:10.1038/bmt.2016.316
PMID:28067889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5332312/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db04/5332312/fabcc7773c94/nihms819976f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db04/5332312/fabcc7773c94/nihms819976f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db04/5332312/fabcc7773c94/nihms819976f1.jpg

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本文引用的文献

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Conditioning chemotherapy dose adjustment in obese patients: a review and position statement by the American Society for Blood and Marrow Transplantation practice guideline committee.肥胖患者的预处理化疗剂量调整：美国血液和骨髓移植学会实践指南委员会的综述与立场声明
Biol Blood Marrow Transplant. 2014 May;20(5):600-16. doi: 10.1016/j.bbmt.2014.01.019. Epub 2014 Jan 23.
2
Effect of the dose per body weight of conditioning chemotherapy on severity of mucositis and risk of relapse after autologous haematopoietic stem cell transplantation in relapsed diffuse large B cell lymphoma.复发弥漫性大B细胞淋巴瘤自体造血干细胞移植中，预处理化疗的每体重剂量对粘膜炎严重程度及复发风险的影响。
Br J Haematol. 2008 Oct;143(2):268-73. doi: 10.1111/j.1365-2141.2008.07342.x. Epub 2008 Aug 10.
3
Prospective oral mucositis audit: oral mucositis in patients receiving high-dose melphalan or BEAM conditioning chemotherapy--European Blood and Marrow Transplantation Mucositis Advisory Group.前瞻性口腔黏膜炎审计：接受大剂量美法仑或BEAM预处理化疗患者的口腔黏膜炎——欧洲血液与骨髓移植学会黏膜炎咨询小组
J Clin Oncol. 2008 Mar 20;26(9):1519-25. doi: 10.1200/JCO.2007.13.6028. Epub 2008 Feb 11.
4
Morbidity and transplant-related mortality of CBV and BEAM preparative regimens for patients with lymphoid malignancies undergoing autologous stem-cell transplantation.接受自体干细胞移植的淋巴系统恶性肿瘤患者采用CBV和BEAM预处理方案的发病率及移植相关死亡率。
Leuk Lymphoma. 2006 Aug;47(8):1488-94. doi: 10.1080/10428190500527769.
5
Effect of body mass index on mortality of patients with lymphoma undergoing autologous hematopoietic cell transplantation.体重指数对接受自体造血细胞移植的淋巴瘤患者死亡率的影响。
Biol Blood Marrow Transplant. 2006 May;12(5):541-51. doi: 10.1016/j.bbmt.2005.12.033.
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Bone Marrow Transplant. 2003 Jun;31(11):961-6. doi: 10.1038/sj.bmt.1704052.
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Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.美国成年人前瞻性队列研究中的超重、肥胖与癌症死亡率
N Engl J Med. 2003 Apr 24;348(17):1625-38. doi: 10.1056/NEJMoa021423.
8
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