Iranmahboob Amir K, Kierans Andrea S, Huang Chenchan, Ream Justin M, Rosenkrantz Andrew B
Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016, United States.
Clin Imaging. 2017 Mar-Apr;42:172-177. doi: 10.1016/j.clinimag.2016.12.007. Epub 2016 Dec 21.
To evaluate whole-pancreas 3D-histogram ADC metrics in acute pancreatitis.
In 41 patients with acute pancreatitis undergoing MRI/MRCP with DWI, 3D-volumes-of-interest encompassing the entire pancreas were placed to derive whole-pancreas histogram ADC metrics.
There were trends toward higher 0-10th percentile ADC, higher 10-25th percentile ADC, lower skewness, and higher kurtosis in patients with new complications (p=0.065-0.095). Conventional mean ADC showed no association with new complications (p=0.203). Kurtosis had highest area-under-the-curve (0.784) for predicting new complications (sensitivity=75.0%; specificity=91.9%).
Findings suggest whole-pancreas histogram ADC metrics assist early management of acute pancreatitis, (e.g., patient selection for more intensive monitoring/intervention).
评估急性胰腺炎中全胰腺三维直方图ADC指标。
对41例接受MRI/MRCP及DWI检查的急性胰腺炎患者，放置包含整个胰腺的三维感兴趣区，以得出全胰腺直方图ADC指标。
新发并发症患者的ADC第0 - 10百分位数、第10 - 25百分位数有升高趋势，偏度降低，峰度升高（p = 0.065 - 0.095）。传统平均ADC与新发并发症无关联（p = 0.203）。峰度预测新发并发症的曲线下面积最高（0.784）（敏感性 = 75.0%；特异性 = 91.9%）。
研究结果表明全胰腺直方图ADC指标有助于急性胰腺炎的早期管理（例如，选择患者进行更强化的监测/干预）。
