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双节段开窗术与半椎板切除术治疗L3-L4和L4-L5双节段椎管狭窄症效果的回顾性配对队列研究

Retrospective Matched-Pair Cohort Study on Effect of Bisegmental Fenestration versus Hemilaminectomy for Bisegmental Spinal Canal Stenosis at L3-L4 and L4-L5.

作者信息

Schüppel Julia, Weber Friedrich

机构信息

Department of Neurosurgery, Medical Research School Duesseldorf, Heilbronn, Germany.

Department of Neurosurgery, Rueckenzentrum, Bergisch, Gladbach, Germany.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2017 Sep;78(5):431-439. doi: 10.1055/s-0036-1597617. Epub 2017 Jan 9.

Abstract

The main symptoms of degenerative lumbar spinal canal stenosis are progressive back pain, spinal claudication, and, occasionally, sensory and motor deficits. Impairments particularly occur during walking, standing, and sitting. Thus social and vocational activities are increasingly restricted, causing considerable suffering for patients. Surgical therapies are superior to conservative ones. This article studies the outcome of 2-level fenestration versus hemilaminectomy for bisegmental spinal stenosis decompression.  This retrospective matched-pair cohort study included a total of 144 patients who underwent surgery for bisegmental spinal stenosis at the levels L3-4 and L4-5 between 2008 and 2012. There were 72 matching pairs that corresponded in sex, year of birth, and width of the stenosed segments. The patients' impairments were reported before, immediately after, and 6 and 12 months after surgery using the Oswestry Disability Questionnaire (ODQ-D) and the EuroQol-5D (EQ-5D). The data were evaluated statistically.  The comparison of both surgical procedures regarding walking ability (walking a distance with and without a walking aid) revealed a significant difference. Patients who underwent hemilaminectomy had better postoperative results. The individual criteria of the ODQ-D and EQ-5D revealed no significant differences between 2-level fenestration and hemilaminectomy; however, there is always significant postoperative improvement in comparison with preoperative status. Age, sex, body mass index, comorbidities, smoking, and alcohol consumption had no influence on the surgical results. The reoperation rate was between 13% and 15% for both surgical techniques, not being significantly different.  Fenestration and hemilaminectomy are equivalent therapies for bisegmental lumbar spinal canal stenosis. Regarding walking, the study revealed better results for hemilaminectomy than for fenestration in this cohort of patients. Pain intensity, personal care, lifting and carrying of objects, sitting, social life, and travel all improved significantly postoperatively as compared with preoperatively. In both groups, health status as the decisive predictor improved considerably after surgery. We could show that both surgical methods result in significant postoperative improvement of all the individual criteria of the ODQ-D and the EQ-5D.

摘要

退行性腰椎管狭窄症的主要症状为进行性背痛、脊髓性间歇性跛行,偶尔还伴有感觉和运动功能障碍。这些功能障碍尤其在行走、站立和坐立时出现。因此,社交和职业活动受到越来越多的限制,给患者带来极大痛苦。手术治疗优于保守治疗。本文研究了双节段椎管狭窄减压的二级开窗术与半椎板切除术的疗效。  这项回顾性配对队列研究共纳入了144例在2008年至2012年间接受L3 - 4和L4 - 5节段双节段椎管狭窄手术的患者。有72对匹配患者,在性别、出生年份和狭窄节段宽度方面相对应。使用Oswestry功能障碍问卷(ODQ - D)和欧洲五维健康量表(EQ - 5D)在手术前、术后即刻、术后6个月和12个月报告患者的功能障碍情况。对数据进行统计学评估。  两种手术方法在行走能力(借助和不借助助行器行走的距离)方面的比较显示出显著差异。接受半椎板切除术的患者术后效果更好。ODQ - D和EQ - 5D的各项具体标准在二级开窗术和半椎板切除术之间未显示出显著差异;然而,与术前状态相比,术后均有显著改善。年龄、性别、体重指数、合并症、吸烟和饮酒对手术结果均无影响。两种手术技术的再次手术率均在13%至15%之间,无显著差异。  开窗术和半椎板切除术是治疗双节段腰椎管狭窄的等效疗法。在行走方面,该研究显示在这组患者中半椎板切除术的效果优于开窗术。与术前相比,疼痛强度、个人护理、提举和搬运物品、坐姿、社交生活以及出行等方面术后均有显著改善。在两组中,作为决定性预测指标的健康状况在术后均有显著改善。我们可以证明,两种手术方法均能使ODQ - D和EQ - 5D的所有具体标准在术后得到显著改善。

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