自由游动金鱼大脑的无线电生理学
Wireless electrophysiology of the brain of freely swimming goldfish.
作者信息
Vinepinsky Ehud, Donchin Opher, Segev Ronen
机构信息
Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel; Department of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
出版信息
J Neurosci Methods. 2017 Feb 15;278:76-86. doi: 10.1016/j.jneumeth.2017.01.001. Epub 2017 Jan 6.
BACKGROUND
Fish are a diverse group of vertebrates with very different brain structures. The study of the neurobiology of fish can thus lead to many important insights on information processing in the brain in a variety of environments.
NEW METHOD
We developed a novel wireless technique to record extracellular neural signal activity in freely behaving fish. The system is based on a data logger and enables continues recording of up to 2.5h.
RESULTS
For proof of concept we recorded from the optic tectum of goldfish. We found correlations between the activity of the optic tectum and the light intensity in the room, as expected.
COMPARISON WITH EXISTING METHODS
Due to the technical difficulties involved in making electrophysiological recordings of behaving aquatic animals, there is no method for recording electrical neural activity from the brain of freely swimming fish.
CONCLUSIONS
This powerful tool should facilitate studies of information processing in behaving fish and other behaving aquatic animals.
背景
鱼类是一类具有非常不同脑结构的多样化脊椎动物。因此，对鱼类神经生物学的研究可以在各种环境中为大脑信息处理带来许多重要见解。
新方法
我们开发了一种新颖的无线技术来记录自由活动鱼类的细胞外神经信号活动。该系统基于一个数据记录器，能够持续记录长达2.5小时。
结果
为了进行概念验证，我们从金鱼的视顶盖进行了记录。正如预期的那样，我们发现视顶盖的活动与室内光强度之间存在相关性。
与现有方法的比较
由于对行为水生动物进行电生理记录存在技术困难，目前没有方法从自由游动鱼类的大脑中记录神经电活动。
结论
这个强大的工具应该有助于对活动鱼类和其他活动水生动物的信息处理进行研究。
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