Witting Michael D
Department of Emergency Medicine, University of Maryland School of Medicine, 110S. Paca St., 6th Floor, Suite 200, Baltimore, MD 21201, United States.
Am J Emerg Med. 2017 Apr;35(4):637-639. doi: 10.1016/j.ajem.2016.12.052. Epub 2016 Dec 23.
Objective The lack of a sensitive, practical bedside test for hypovolemia has rekindled interest in the shock index (heart rate divided by systolic blood pressure). Here, we compare the effect of blood donation on standing shock index values with its effect on values for the supine shock index and orthostatic change in shock indicies (OCSI).
This is a re-analysis of data collected for an earlier report. Data were available from 292 adults below age 65 and 44 adults ages 65 and over, donating 450mL of blood. We obtained supine and standing vital signs before and after donation and then calculated 95% confidence intervals for differences based on the t-distribution.
Blood donation resulted in a mean increase in the standing shock index of 0.09 [95% CI, 0.08-0.11] in younger adults and 0.08 [95% CI, 0.05-0.11] in older adults. These changes were similar to those noted for OCSI (young, 95% CI, 0.08-0.10; old, 95% CI, 0.04-0.10). Supine shock index values did not change with donation in younger donors (mean difference 0.0 [95% CI, 0.0-0.01]) or older donors (mean difference 0.0 [95% CI, -0.01-0.03]).
Blood donation does not affect the supine shock index, but it does result in changes in standing shock index that are similar to changes in more complicated orthostatic vital signs.
目的 缺乏一种用于评估血容量不足的敏感、实用的床旁检测方法,这重新引发了人们对休克指数(心率除以收缩压)的兴趣。在此,我们比较献血对站立位休克指数值的影响及其对仰卧位休克指数值和休克指数体位性变化(OCSI)的影响。
这是对之前一份报告所收集数据的重新分析。数据来自292名65岁以下的成年人和44名65岁及以上的成年人,他们均捐献了450毫升血液。我们在献血前后获取了仰卧位和站立位生命体征,然后根据t分布计算差异的95%置信区间。
献血导致年轻成年人站立位休克指数平均增加0.09[95%置信区间,0.08 - 0.11],老年成年人增加0.08[95%置信区间,0.05 - 0.11]。这些变化与OCSI的变化相似(年轻组,95%置信区间,0.08 - 0.10;老年组,95%置信区间,0.04 - 0.10)。年轻献血者仰卧位休克指数值在献血后未发生变化(平均差异0.0[95%置信区间,0.0 - 0.01]),老年献血者也是如此(平均差异0.0[95%置信区间, - 0.01 - 0.03])。
献血不影响仰卧位休克指数,但会导致站立位休克指数发生变化,且这种变化与更复杂的体位性生命体征变化相似。