Rosenblatt K A, Weiss N S, Schwartz S M
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle 98105.
Gynecol Oncol. 1989 Nov;35(2):236-9. doi: 10.1016/0090-8258(89)90051-6.
Incidence rates were examined for epithelial malignant fallopian tube neoplasms diagnosed between 1973 and 1984 and reported to nine population-based cancer registries in the United States. The average annual incidence was 3.6 per million women per year and there was no evidence of a change in the rate during the study period. Age-specific incidence followed a pattern similar to that observed for ovarian and endometrial neoplasms, rising rapidly during the reproductive years and flattening out thereafter. The incidence rate varied only slightly by race, with whites having a higher rate than blacks. Considerable variation in incidence was observed among the registries. While this could have been due to true regional differences in incidence, we cannot rule out the possibility that misclassification of fallopian tube tumors as ovarian tumors was responsible. Further investigations into the etiology of fallopian tube neoplasms should focus on the role of reproductive factors that have previously been reported as risk factors for ovarian and endometrial neoplasms.
对1973年至1984年间诊断出的上皮性恶性输卵管肿瘤的发病率进行了研究,这些病例已上报给美国9个基于人群的癌症登记处。每年每百万女性的平均发病率为3.6例,且在研究期间没有证据表明发病率有所变化。特定年龄发病率遵循与卵巢和子宫内膜肿瘤相似的模式,在生育期迅速上升,之后趋于平稳。发病率在种族间仅有轻微差异,白人的发病率高于黑人。各登记处之间观察到发病率存在相当大的差异。虽然这可能是由于发病率存在真正的地区差异,但我们不能排除将输卵管肿瘤误诊为卵巢肿瘤的可能性。对输卵管肿瘤病因的进一步研究应聚焦于先前已被报道为卵巢和子宫内膜肿瘤危险因素的生殖因素的作用。