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基于奖品强化可卡因使用者戒断的应急管理对可卡因渴望的疗效。

The Efficacy of Contingency Management on Cocaine Craving, using Prize-based Reinforcement of Abstinence in Cocaine Users.

作者信息

Pirnia Bijan, Tabatabaei Seyed Kazem Rasoulzadeh, Tavallaii Abbas, Soleimani Ali Akbar, Pirnia Kambiz

机构信息

PhD. Student of Clinical Psychology, Department of Psychology, Faculty of Humanities, University of Science and Culture, Tehran, Iran.

Ph.D. of Psychology, Associate Professor, Department of Psychology, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.

出版信息

Electron Physician. 2016 Nov 25;8(11):3214-3221. doi: 10.19082/3214. eCollection 2016 Nov.

Abstract

INTRODUCTION

Contingency management (CM) is one of the most common therapies in the domain of drug addiction. This study has been carried out with the purpose of evaluating the efficacy of contingency management intervention.

METHOD

In an experimental design, between December 15, 2014 and November 20, 2015, fifty men (between 18 and 31 with an average age of 24.6) with a history of cocaine use, were selected voluntarily and were randomly assigned into two groups of CM and control group. The CM group were awarded coupons for negative urine tests, over a period of twelve weeks. The urine tests were taken from the participants twice per week, with cutoff concentrations for positive set at 300 ng/ml and self-reporting index of cocaine craving (response rate = 96%) were evaluated in two phase, through pretest and posttest measures. The data were analyzed by parametric covariance test. Additionally, the qualitative data, resulted from demographic measures, were coded and were analyzed with the help of an analysis instrument of qualitative data i.e. ATLAS.ti-5.2.

RESULTS

The primary outcome was the number of negative urine tests and the secondary outcome included the cocaine usage craving index over twelve weeks. The mean of (95% of confidence) number of negative cocaine urine tests was 15.4 (13.1-17.8) in the CM group and 19.7 (17.7-21.6) in the control group (P = 0.049). Also, results showed that CM has a significant effect on reducing craving (p<0.01).

CONCLUSION

The findings of this study, while having practical aspects in this domain, can be valuable in planning remedial procedures.

摘要

引言

应急管理(CM)是药物成瘾领域最常用的治疗方法之一。本研究旨在评估应急管理干预的效果。

方法

在一项实验设计中,于2014年12月15日至2015年11月20日期间,五十名有可卡因使用史的男性(年龄在18至31岁之间,平均年龄24.6岁)自愿入选,并随机分为CM组和对照组。CM组在十二周的时间里,因尿液检测呈阴性而获得优惠券。参与者每周接受两次尿液检测,阳性的临界浓度设定为300纳克/毫升,并通过预测试和后测试措施分两个阶段评估可卡因渴望的自我报告指数(反应率=96%)。数据采用参数协方差检验进行分析。此外,对人口统计学测量产生的定性数据进行编码,并借助定性数据分析工具即ATLAS.ti-5.2进行分析。

结果

主要结果是尿液检测呈阴性的次数,次要结果包括十二周内的可卡因使用渴望指数。CM组可卡因尿液检测呈阴性的平均次数(95%置信区间)为15.4(13.1-17.8),对照组为19.7(17.7-21.6)(P = 0.049)。此外,结果表明CM对减少渴望有显著效果(p<0.01)。

结论

本研究的结果,在该领域具有实际意义,对规划补救程序可能具有重要价值。

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