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继发于肾衰竭的睾丸网获得性囊性变。

Acquired cystic transformation of the rete testis secondary to renal failure.

作者信息

Nistal M, Santamaria L, Paniagua R

机构信息

Department of Morphology, School of Medicine, Autonomous University, Madrid, Spain.

出版信息

Hum Pathol. 1989 Nov;20(11):1065-70. doi: 10.1016/0046-8177(89)90224-4.

DOI:10.1016/0046-8177(89)90224-4
PMID:2807269
Abstract

The histologic study of testicular specimens from 218 consecutive autopsies revealed a cystic transformation of the rete testis in 26 men. Serial sections of the testes, epididymides, and spermatic cords of these men were studied by light microscopy. In 15 cases, the rete testis dilation was caused by obstruction of the epididymis. In five cases, the dilation was due to obstruction of the intratesticular excretory ducts caused by varicocele. In the remaining six men, no evidence of obstructive processes was found. These six patients had been diagnosed with renal failure and underwent hemodialysis. The rete testis in these men showed dilated channels lined by a high columnar or pseudostratified epithelium. They contained spermatozoa, with a proteinaceous material and calcium oxalate crystals. The ductuli efferents showed eosinophilic granules in their epithelial cells and their lumen contained spermatids, spermatozoa, cell remnants, calcium oxalate crystals, and multinucleate giant cells. These rete testis lesions are similar to those previously reported in the kidney of hemodialyzed patients.

摘要

对218例连续尸检的睾丸标本进行组织学研究发现,26名男性存在睾丸网的囊性变。对这些男性的睾丸、附睾和精索进行连续切片,通过光学显微镜进行研究。在15例中,睾丸网扩张是由附睾梗阻引起的。在5例中,扩张是由于精索静脉曲张导致睾丸内排泄管梗阻所致。在其余6名男性中,未发现梗阻过程的证据。这6名患者被诊断为肾衰竭并接受了血液透析。这些男性的睾丸网显示出由高柱状或假复层上皮衬里的扩张通道。它们含有精子、一种蛋白质物质和草酸钙晶体。输出小管的上皮细胞显示嗜酸性颗粒,其管腔内含有精子细胞、精子、细胞残余物、草酸钙晶体和多核巨细胞。这些睾丸网病变与先前在接受血液透析患者的肾脏中报道的病变相似。

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Spermatogenesis. 2014 Dec 31;4(2):e979103. doi: 10.4161/21565562.2014.979103. eCollection 2014 May-Aug.
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Secondary oxalosis and sperm granuloma of the epididymis.继发性草酸中毒与附睾精子肉芽肿。
J Clin Pathol. 1994 May;47(5):470-1. doi: 10.1136/jcp.47.5.470.
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Cystic dysplasia of the testis. Sonographic features with pathologic correlation.
睾丸囊性发育异常。超声特征与病理对照
Pediatr Radiol. 1991;21(7):501-3. doi: 10.1007/BF02011723.