间质 MicroRNA 功能多元化。
Mesenchymal MicroRNA Function Branches Out.
机构信息
Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Craniofacial Anomalies Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA; Department of Endodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA.
Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Craniofacial Anomalies Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA; Department of Prosthodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA.
出版信息
Dev Cell. 2017 Jan 9;40(1):1-2. doi: 10.1016/j.devcel.2016.12.018.
Significant amounts of microRNAs (miRs) are detected in exosomes, but their function during fetal development is poorly understood. In this issue of Developmental Cell, Hayashi et al. (2017) show that exosomal miRs secreted by mesenchymal cells can regulate epithelial KIT progenitor cell expansion during murine salivary gland organogenesis.
大量的 microRNAs（miRs）存在于外泌体中，但其在胎儿发育过程中的功能尚不清楚。在本期《发育细胞》中，Hayashi 等人（2017）表明，间充质细胞分泌的外泌体 miR 可以调节小鼠唾液腺器官发生过程中的上皮 KIT 祖细胞的扩增。
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