Li Lian, Zhang Shuang, Huang Yubei, Chen Kexin
Department of Epidemiology and Biostatistics, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Tianjin Center for Disease Control and Prevention, Tianjin, China.
J Paediatr Child Health. 2017 Apr;53(4):378-385. doi: 10.1111/jpc.13434. Epub 2017 Jan 10.
Childhood obesity is a major public problem worldwide, and sleep duration may be associated with childhood obesity. We conducted a systematic review and meta-analysis of prospective cohort studies to estimate the associations between sleep duration and obesity/body mass index (BMI) in children.
PubMed, Embase and the Cochrane Library were searched. For the meta-analysis, the pooled relative risk (RR) and 95% confidence intervals (CI) were estimated to reveal the association between short sleep duration and obesity. For the review, the outcomes focused on BMI change or subsequent BMI status.
A total of 12 studies (15 populations) met the criteria for inclusion in the meta-analysis. Short sleep duration was significantly associated with obesity (RR: 1.45; 95% CI: 1.14-1.85). After excluding two cohorts that substantially affected the heterogeneity, the pooled results remained significant (RR: 1.30; 95% CI: 1.20-1.42), and the association was not substantially altered in the subgroup analysis. In addition, we summarised 24 studies that met the criteria for our review of the relationship between sleeping and BMI.
The present meta-analysis indicated that short sleep duration increased the risk of childhood obesity. Public health efforts that encourage children to have sufficient sleep time may be important in combating obesity.
儿童肥胖是全球主要的公共卫生问题，睡眠时间可能与儿童肥胖有关。我们对前瞻性队列研究进行了系统评价和荟萃分析，以评估睡眠时间与儿童肥胖/体重指数（BMI）之间的关联。
检索了PubMed、Embase和Cochrane图书馆。对于荟萃分析，估计合并相对风险（RR）和95%置信区间（CI），以揭示短睡眠时间与肥胖之间的关联。对于综述，结果集中在BMI变化或随后的BMI状态。
共有12项研究（15个群体）符合纳入荟萃分析的标准。短睡眠时间与肥胖显著相关（RR：1.45；95%CI：1.14-1.85）。排除两个对异质性有重大影响的队列后，合并结果仍然显著（RR：1.30；95%CI：1.20-1.42），且该关联在亚组分析中未发生实质性改变。此外，我们总结了24项符合我们对睡眠与BMI关系综述标准的研究。
目前的荟萃分析表明，短睡眠时间会增加儿童肥胖的风险。鼓励儿童有足够睡眠时间的公共卫生措施可能对对抗肥胖很重要。
