Selvakumar R, John T J
Indian J Med Res. 1989 Jul;89:217-20.
The immunogenic and protective efficacy of a new, killed and purified rabies virus vaccine prepared in chick embryo fibroblast cell culture, has been evaluated. Vaccine was administered on days 0, 3, 7, 14, 30 and 90 to 29 subjects who were bitten by dogs. Persons bitten on the face, neck or hand were also given rabies immunoglobulin. Virus neutralizing antibody was measured on serially collected sera. On day 14, all 26 subjects who were tested had developed protective levels of antibody. High levels of antibody were maintained through day 105. No adverse reactions to the vaccine was reported by the subjects.
对在鸡胚成纤维细胞培养物中制备的一种新的灭活纯化狂犬病病毒疫苗的免疫原性和保护效力进行了评估。在第0、3、7、14、30和90天，给29名被狗咬伤的受试者接种了疫苗。面部、颈部或手部被咬伤的人还注射了狂犬病免疫球蛋白。对连续采集的血清进行病毒中和抗体检测。在第14天，所有接受检测的26名受试者都产生了具有保护水平的抗体。在第105天之前，抗体水平一直维持在较高水平。受试者未报告对该疫苗有不良反应。
