Staanum Peter Frøhlich, Arveschoug Anne Kirstine, Kramer Stine Maria Jentoft, Nielsen Jens Erik, Nielsen Dennis Tønner, Ott Peter, Grønbæk Henning, Villadsen Gerda Elisabeth
Ugeskr Laeger. 2017 Jan 2;179(1).
Selective internal radiation therapy (SIRT) of hepatocellular carcinoma has been introduced at Aarhus University Hospital. 90Y-microspheres are implanted in the tumour by catheterization of the tumour feeding liver artery. Pretreatment angiography and test treatment using 99mTc-labelled particles followed by scintigraphy ensure a feasible and effective treatment. Post-treatment imaging of radiation from 90Y visualize the localization of microspheres. Currently, SIRT is also applied for liver metastases of neuroendocrine tumours. Future indications may include other liver tumours and metastases.
奥胡斯大学医院已引入肝细胞癌的选择性内放射治疗(SIRT)。通过对肿瘤供血肝动脉进行导管插入术,将90Y微球植入肿瘤。治疗前血管造影和使用99mTc标记颗粒的试验性治疗,随后进行闪烁显像,可确保治疗可行且有效。90Y辐射的治疗后成像可显示微球的定位。目前,SIRT也应用于神经内分泌肿瘤的肝转移。未来的适应症可能包括其他肝脏肿瘤和转移瘤。