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体外冲击波碎石术中依诺沙星的抗生素预防作用

[Antibiotic prophylaxis with enoxacin in extracorporeal shockwave lithotripsy].

作者信息

Knipper A, Böhle A, Pensel J, Hofstetter A G

机构信息

Klinik für Urologie, Medizinische Universität Lübeck.

出版信息

Infection. 1989;17 Suppl 1:S37-8. doi: 10.1007/BF01643635.

Abstract

According to literature, 16 to 35% of operatively removed renal stones harbour bacteria. The efficacy of antibiotic prophylaxis with enoxacin in reducing the rate of bacteriuria after extracorporeal shock wave lithotripsy (ESWL) was investigated in a prospective randomized study. Twenty-five patients received a single 400 mg dose of enoxacin one hour before ESWL, 25 patients did not receive an antibiotic. It was found that a single 400 mg dose of enoxacin one hour before ESWL can reduce the rate of bacteriuria significantly.

摘要

根据文献记载,手术取出的肾结石中有16%至35%带有细菌。在一项前瞻性随机研究中,对依诺沙星预防性使用抗生素以降低体外冲击波碎石术(ESWL)后菌尿发生率的疗效进行了调查。25名患者在ESWL前1小时接受单次400毫克依诺沙星剂量,25名患者未接受抗生素治疗。结果发现,在ESWL前1小时单次服用400毫克依诺沙星可显著降低菌尿发生率。

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