基于氟达拉滨的诱导治疗对FLT3- /NPM1+细胞遗传学正常的急性髓系白血病预后的影响 - Suppr

Impact of fludarabine-based induction therapy on outcome of FLT3-/NPM1+ cytogenetically normal acute myeloid leukemia.

作者信息

Tiribelli Mario, Geromin Antonella, Damiani Daniela

机构信息

Division of Hematology and BMT, Department of Experimental and Clinical Medical Sciences, Azienda Sanitaria Universitaria Integrata, Udine, Italy.

出版信息

Am J Hematol. 2017 Apr;92(4):E45-E47. doi: 10.1002/ajh.24651. Epub 2017 Feb 13.

DOI:10.1002/ajh.24651

PMID:28076884

Abstract

摘要

相似文献

Impact of fludarabine-based induction therapy on outcome of FLT3-/NPM1+ cytogenetically normal acute myeloid leukemia.基于氟达拉滨的诱导治疗对FLT3- /NPM1+细胞遗传学正常的急性髓系白血病预后的影响

Am J Hematol. 2017 Apr;92(4):E45-E47. doi: 10.1002/ajh.24651. Epub 2017 Feb 13.

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.细胞遗传学正常的急性髓系白血病中的突变与治疗结果

N Engl J Med. 2008 May 1;358(18):1909-18. doi: 10.1056/NEJMoa074306.

Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.异基因干细胞移植可提高具有高突变型FLT3-ITD等位基因比例特征的急性髓系白血病患者的生存率。

Biol Blood Marrow Transplant. 2016 Mar;22(3):462-9. doi: 10.1016/j.bbmt.2015.10.023. Epub 2015 Nov 10.

Prognostic implications of NPM1 mutations and FLT3 internal tandem duplications in Egyptian patients with cytogenetically normal acute myeloid leukemia.NPM1突变和FLT3内部串联重复在埃及细胞遗传学正常的急性髓系白血病患者中的预后意义

Hematology. 2014 Jan;19(1):22-30. doi: 10.1179/1607845413Y.0000000085. Epub 2013 Nov 25.

Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the interaction with FLT3 and NPM1 mutations.CEBPA 突变对年轻急性髓系白血病患者大队列的预后意义：双 CEBPA 突变的影响以及与 FLT3 和 NPM1 突变的相互作用。

J Clin Oncol. 2010 Jun 1;28(16):2739-47. doi: 10.1200/JCO.2009.26.2501. Epub 2010 May 3.

Clinical impact of nucleophosmin mutations and Flt3 internal tandem duplications in patients older than 60 yr with acute myeloid leukaemia.60岁以上急性髓系白血病患者中核磷蛋白突变和Flt3内部串联重复的临床影响

Eur J Haematol. 2008 Mar;80(3):208-15. doi: 10.1111/j.1600-0609.2007.01019.x.

Dynamics of molecular response in AML patients with NPM1 and FLT3 mutations undergoing allogeneic stem cell transplant.

Bone Marrow Transplant. 2017 Aug;52(8):1187-1190. doi: 10.1038/bmt.2017.82. Epub 2017 Jun 5.

Transplant outcomes of the triple-negative NPM1/FLT3-ITD/CEBPA mutation subgroup are equivalent to those of the favourable ELN risk group, but significantly better than the intermediate-I risk group after allogeneic transplant in normal-karyotype AML.在正常核型急性髓系白血病（AML）中，三阴性NPM1/FLT3-ITD/CEBPA突变亚组的移植结局与良好ELN风险组相当，但在异基因移植后明显优于中危-I风险组。

Ann Hematol. 2016 Mar;95(4):625-35. doi: 10.1007/s00277-015-2580-z. Epub 2015 Dec 22.

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia.年龄、NPM1和FLT3等位基因比例对急性髓系白血病患者的影响。

Blood. 2018 Mar 8;131(10):1148-1153. doi: 10.1182/blood-2017-09-807438. Epub 2017 Nov 28.

Favorable outcome in patients with acute myelogenous leukemia with the nucleophosmin gene mutation autografted after conditioning with high-dose continuous infusion of idarubicin and busulfan.经大剂量连续输注伊达比星和白消安预处理后，伴有核仁磷酸蛋白基因突变的急性髓细胞白血病患者进行自体移植后获得良好结果。

Biol Blood Marrow Transplant. 2010 Jul;16(7):1018-24. doi: 10.1016/j.bbmt.2010.02.011. Epub 2010 Feb 19.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Impact of fludarabine-based induction therapy on outcome of FLT3-/NPM1+ cytogenetically normal acute myeloid leukemia.

作者信息

机构信息

出版信息

相似文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献