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一例被误诊为结核性脊柱炎的暗色丝孢霉性腰椎间盘炎罕见病例。

A Rare Case of Pheohyphomycotic Lumbar Spondylodiscitis Mistreated as Koch's Spine.

作者信息

Goel Shakti A, Modi Hitesh N, Desai Yatin J, Thaker Harshal P

机构信息

Department of Orthopaedics and Spine Surgery, Zydus Hospitals and Healthcare Research Pvt. Ltd., Thaltej, Ahmedabad, Gujarat, India.

Dr. Harshal Thaker's Clinic, Ambawadi, Ahmedabad, Gujarat, India.

出版信息

Case Rep Orthop. 2016;2016:8705204. doi: 10.1155/2016/8705204. Epub 2016 Dec 18.

Abstract

Pheohyphomycosis is an uncommon infection and its association in spondylodiscitis has not yet been reported. The purpose of this case report is to describe a rare case of Pheohyphomycotic spondylodiscitis and methods to diagnose and manage the patient with less invasive techniques. A 29-year-old male patient presented to the outpatient department with complaints of gradually increasing low back pain with bilateral lower limbs radicular pain since one and a half years. He had associated fever, weight loss, voice changes, and dry, scaly, erythematous skin with elevated ESR. The patient had been taking anti-Koch's therapy since 1 year with little relief in pain and no radiological improvement. Percutaneous pedicle biopsy of L4 vertebra was taken under local anaesthesia and confirmed Pheohyphomycosis which was treated with antifungal medications. The patient showed sequential improvement with long term antifungal treatment. He was eventually able to walk independently without support.

摘要

暗色丝孢霉病是一种罕见的感染,其与脊椎间盘炎的关联尚未见报道。本病例报告的目的是描述一例罕见的暗色丝孢霉性脊椎间盘炎病例以及采用微创技术诊断和治疗该患者的方法。一名29岁男性患者因自一年半前开始出现逐渐加重的下腰痛伴双侧下肢放射性疼痛而就诊于门诊。他伴有发热、体重减轻、声音改变以及干燥、鳞屑状、红斑性皮肤,血沉升高。该患者自一年前开始接受抗结核治疗,但疼痛缓解甚微,影像学上也无改善。在局部麻醉下对L4椎体进行了经皮椎弓根活检,确诊为暗色丝孢霉病,随后用抗真菌药物进行治疗。经过长期抗真菌治疗,患者病情逐步改善。他最终能够独立行走而无需支撑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4374/5203892/3d7da77e994c/CRIOR2016-8705204.001.jpg

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