Huang Yuhui, Sumida Mami, Kumazoe Motofumi, Sugihara Kaori, Suemasu Yumi, Yamada Shuhei, Yamashita Shuya, Miyakawa Jyunichi, Takahashi Takashi, Tanaka Hiroshi, Fujimura Yoshinori, Tachibana Hirofumi
Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro, Tokyo 152-8552, Japan.
Chem Commun (Camb). 2017 Feb 7;53(12):1941-1944. doi: 10.1039/c6cc09504f.
Green tea polyphenol (-)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.
绿茶多酚（-）-表没食子儿茶素-3-O-没食子酸酯（EGCG）被认为可激活其细胞表面传感受体67 kDa层粘连蛋白受体（67LR）。然而，EGCG激活67LR的作用尚不清楚。在此我们表明，EGCG在其表面受体67LR上形成寡聚物。
