Brauneis J W, Laskawi R, Schröder M, Göhde W
HNO-Klinik Universität Göttingen.
HNO. 1989 Sep;37(9):369-72.
Tumour biopsies of 93 patients with head and neck malignancy were analysed by cytophotometry. Ploidy and the proportion of cells in S-phase were measured. Tumours were classified as proliferative if the S-phase fraction was greater than 8%; the rest were classified as being less proliferative. Proliferative tumours produce local and distant metastases earlier and more frequently, so that the proportion of cells in S-phase is of prognostic importance. The response to chemotherapy of irradiation was no different in either group.
对93例头颈部恶性肿瘤患者的肿瘤活检组织进行了细胞光度测定分析。测量了倍性和S期细胞比例。如果S期分数大于8%，肿瘤被分类为增殖性；其余的被分类为增殖性较低。增殖性肿瘤更早且更频繁地产生局部和远处转移，因此S期细胞比例具有预后重要性。两组对化疗或放疗的反应没有差异。
