Department of Nuclear Medicine, Mersin State Hospital, Mersin, Turkey.
Department of Nuclear Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Turk J Med Sci. 2016 Dec 20;46(6):1829-1837. doi: 10.3906/sag-1507-162.
BACKGROUND/AIM: Breast lesions that are not palpable on physical examination but considered suspicious for malignancy on mammography or ultrasonography should be marked before surgery. Wire-guided localization (WGL) is the most frequently used method for preoperative marking of nonpalpable breast lesions (NPBLs). An alternative is marking by a radioactive agent (radio-guided occult lesion localization; ROLL). The present study aimed to compare WGL and ROLL for preoperative marking.
The study included 25 patients marked by ROLL and 11 patients marked by WGL. The groups were compared in terms of patient and lesion characteristics, method-related characteristics, hospital stay duration, complications, cosmetic outcomes, and rate of correct marking.
Suspicious lesions were marked with a success rate of 95.6% by ROLL and 100% by WGL. Complications and pain sensation rates were found significantly lower in the ROLL group compared to WGL. Although ROLL was considered more advantageous in terms of hospital stay duration, positive surgical margins, cosmetic outcomes, and excision duration, the differences between the groups were not statistically significant.
ROLL, which is a simple, comfortable, and reliable method, could be used as an alternative to the WGL in preoperative marking of NPBLs.
背景/目的:对于临床上触诊阴性但在乳腺 X 线摄影或超声检查中怀疑为恶性的乳腺病变,应在术前进行标记。导丝引导定位(WGL)是术前标记不可触及性乳腺病变(NPBL)最常用的方法。另一种方法是放射性示踪剂标记(放射性隐灶定位;ROLL)。本研究旨在比较 WGL 和 ROLL 用于术前标记的效果。
该研究纳入了 25 例 ROLL 标记患者和 11 例 WGL 标记患者。比较了两组患者和病变特征、方法相关特征、住院时间、并发症、美容效果以及正确标记率。
ROLL 标记成功率为 95.6%,WGL 标记成功率为 100%。ROLL 组的并发症和疼痛发生率明显低于 WGL 组。尽管 ROLL 在住院时间、阳性切缘、美容效果和切除时间方面被认为更有优势,但组间差异无统计学意义。
ROLL 是一种简单、舒适、可靠的方法,可作为 NPBL 术前 WGL 的替代方法。