School of Physical Therapy and Rehabilitation, Dokuz Eylül University, İzmir, Turkey.
Department of Cardiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Turk J Med Sci. 2016 Dec 20;46(6):1658-1664. doi: 10.3906/sag-1505-96.
BACKGROUND/AIM: The aims of the present study were to assess the relationship between the distance walked during the 6-min walk test (6MWT) and exercise capacity as determined by cardiopulmonary exercise testing (CPET) in patients with pulmonary arterial hypertension (PAH) and to investigate the prognostic value of the 6MWT in comparison to clinical parameters of CPET and echocardiography findings.
Thirty PAH patients participated in the study. Subject characteristics and New York Heart Association (NYHA) classifications were recorded. All subjects completed the 6MWT and CPET. Relationships among the variables were analyzed by the Pearson correlation test. Correlation coefficients between 6MWT distance and other variables were determined by linear regression analysis.
Distance walked in the 6MWT was significantly correlated with the following exercise parameters: peak oxygen consumption, work load, and metabolic equivalents. Additionally, cardiac index was correlated with peak oxygen consumption and metabolic equivalents. We also showed that cardiac index and age were two significant determinants for exercise performance, accounting for 35.4% of the variance in the 6MWT.
The 6MWT provides information that may be a better index for the patient's NYHA functional class determination than maximal exercise testing.
背景/目的：本研究旨在评估肺动脉高压（PAH）患者 6 分钟步行试验（6MWT）中行走的距离与心肺运动试验（CPET）确定的运动能力之间的关系，并探讨 6MWT 与 CPET 和超声心动图检查的临床参数相比的预后价值。
30 名 PAH 患者参与了这项研究。记录了患者的特征和纽约心脏协会（NYHA）分类。所有患者均完成了 6MWT 和 CPET。通过 Pearson 相关检验分析变量之间的关系。通过线性回归分析确定 6MWT 距离与其他变量之间的相关系数。
6MWT 中行走的距离与以下运动参数显著相关：峰值耗氧量、工作量和代谢当量。此外，心指数与峰值耗氧量和代谢当量相关。我们还表明，心指数和年龄是运动表现的两个重要决定因素，占 6MWT 变异的 35.4%。
6MWT 提供的信息可能比最大运动测试更能更好地反映患者的 NYHA 功能分类。
