Fu Jack B, Lee Jay, Shin Ben C, Silver Julie K, Smith Dennis W, Shah Jatin J, Bruera Eduardo
Department of Palliative, Rehabilitation and Integrative Medicine, Unit 1414, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030(∗).
Department of Exercise and Sports Sciences, New Mexico Highlands University, Las Vegas, NM(†).
PM R. 2017 Jun;9(6):571-578. doi: 10.1016/j.pmrj.2016.12.007. Epub 2017 Jan 8.
Pancytopenia, immunosuppression, and other factors may place patients with multiple myeloma at risk for medical complications. These patients often require inpatient rehabilitation. No previous studies have looked at risk factors for return to the primary acute care service of this patient population.
To determine the percentage of and factors associated with return to the primary acute care service of multiple myeloma rehabilitation inpatients.
Retrospective review.
Acute inpatient rehabilitation unit within a National Cancer Institute Comprehensive Cancer Center.
All patients with multiple myeloma admitted to the inpatient rehabilitation unit between March 1, 2004, and February 28, 2015.
Return to the primary acute care service was analyzed with demographic information, multiple myeloma characteristics, medications, laboratory values, and hospital admission characteristics.
One hundred forty-three inpatient rehabilitation admissions were found during the study period. After we removed multiple admissions of the same patients and planned transfers to the primary acute care service, 122 admissions were analyzed. Thirty-two (26%) patients transferred back to the primary acute care service for unplanned reasons. Multivariate analysis revealed male gender and thrombocytopenia as significantly associated with return to the primary acute care service. The median survival of patients who transferred back to the inpatient primary acute care service was 180 days versus 550 days for those who did not (P < .001).
Because of their medical fragility, clinicians caring for rehabilitation inpatients with multiple myeloma should maintain close contact with the primary oncology service. Factors associated with an increased risk of transfer back to the primary acute care service include male gender and thrombocytopenia.
IV.
全血细胞减少、免疫抑制及其他因素可能使多发性骨髓瘤患者面临发生医学并发症的风险。这些患者常需要住院康复治疗。此前尚无研究探讨该患者群体返回初级急性护理服务机构的风险因素。
确定多发性骨髓瘤康复住院患者返回初级急性护理服务机构的比例及相关因素。
回顾性研究。
国立癌症研究所综合癌症中心内的急性住院康复单元。
2004年3月1日至2015年2月28日期间入住住院康复单元的所有多发性骨髓瘤患者。
结合人口统计学信息、多发性骨髓瘤特征、用药情况、实验室检查值及住院特征分析返回初级急性护理服务机构的情况。
研究期间共发现143例住院康复病例。在排除同一患者的多次住院情况及计划转至初级急性护理服务机构的病例后,对122例住院病例进行了分析。32例(26%)患者因非计划原因转回初级急性护理服务机构。多因素分析显示,男性和血小板减少与返回初级急性护理服务机构显著相关。转回住院初级急性护理服务机构的患者中位生存期为180天,未转回者为550天(P < .001)。
鉴于多发性骨髓瘤康复住院患者身体状况脆弱,照料他们的临床医生应与初级肿瘤服务机构保持密切联系。与转回初级急性护理服务机构风险增加相关的因素包括男性和血小板减少。
四级。