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重度主动脉瓣反流患者行主动脉瓣置换术后左心室早期重塑的频率及其在每搏量≥97ml患者与每搏量<97ml患者之间的比较。

Frequency of early remodeling of left ventricle and its comparison between patients with stroke volume ≥97 Ml versus patients with stroke volume <97 Ml after aortic valve replacement for severe aortic regurgitation.

作者信息

Ali Rizvi Hafiz Muhammad Farhan, Khalid Zaigham Rasool, Baksh Allah, Raza Baig Mirza Ahmad

机构信息

Hafiz Muhammad Farhan Ali Rizvi, FCPS CS. Senior Registrar Cardiac Surgery, Pakistan.

Zaigham Rasool Khalid, FCPS CS. Senior Registrar Pediatric Cardiac Surgery, Pakistan.

出版信息

Pak J Med Sci. 2016 Nov-Dec;32(6):1360-1363. doi: 10.12669/pjms.326.11173.

Abstract

OBJECTIVES

To evaluate the frequency of early remodeling in patients of severe aortic regurgitation after aortic valve replacement and to see the incidence of early remodeling in patients with stroke volume >97 ml versus < 97 ml before aortic valve replacement.

METHOD

This was a prospective comparative study conducted from August 2013 to December 2014 in a tertiary care hospital. Fifty seven (57) patients of isolated chronic aortic regurgitation were included in this study. SPSS v23 was used for data analysis. Independent sample t-test was used for analysis of continuous variables and chi-square test for qualitative variables.

RESULTS

Out of fifty seven patients, early remodeling occurred in 34 (59.64%) patients after surgery. The mean pre-operative stroke volume of patient in whom remodeling occurred was 110.3+9.66 ml while mean pre-operative stroke volume of patients who did not undergo remodeling was 86.65+7.63 ml. There were 28 (82.4%) patients with stroke volume >97 ml in whom Remodeling occurred where as in patients with stroke volume <97 ml remodeling occurred only in 6 (17.6%) patients (p value 0.004). There was no in-hospital mortality.

CONCLUSION

There is an association between stroke volume and early LV remodeling after Aortic valve replacement. Stroke volume >97 ml is a good predictor of early LV remodeling.

摘要

目的

评估重度主动脉瓣关闭不全患者主动脉瓣置换术后早期重塑的发生率,并观察主动脉瓣置换术前每搏输出量>97ml与<97ml的患者早期重塑的发生率。

方法

这是一项于2013年8月至2014年12月在一家三级医疗中心进行的前瞻性对照研究。本研究纳入了57例单纯慢性主动脉瓣关闭不全患者。采用SPSS v23进行数据分析。连续变量分析采用独立样本t检验,定性变量分析采用卡方检验。

结果

57例患者中,34例(59.64%)术后发生早期重塑。发生重塑患者的术前平均每搏输出量为110.3+9.66ml,未发生重塑患者的术前平均每搏输出量为86.65+7.63ml。每搏输出量>97ml的患者中有28例(82.4%)发生重塑,而每搏输出量<97ml的患者中只有6例(17.6%)发生重塑(p值0.004)。院内无死亡病例。

结论

主动脉瓣置换术后每搏输出量与左心室早期重塑之间存在关联。每搏输出量>97ml是左心室早期重塑的良好预测指标。

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