Wooding Steven, Hanney Stephen, Pollitt Alexandra, Buxton Martin, Grant Jonathan
Rand Health Q. 2011 Mar 1;1(1):16. eCollection 2011 Spring.
This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the research, researcher or environment that are associated with high or low impact. The project is a case study-based review of 29 cardiovascular and stroke research grants, funded in Australia, Canada and UK between 1989 and 1993. The case studies focused on the individual grants but considered the development of the investigators and ideas involved in the research projects from initiation to the present day. Grants were selected through a stratified random selection approach that aimed to include both high- and low-impact grants. The key messages are as follows: 1) The cases reveal that a large and diverse range of impacts arose from the 29 grants studied. 2) There are variations between the impacts derived from basic biomedical and clinical research. 3) There is no correlation between knowledge production and wider impacts 4) The majority of economic impacts identified come from a minority of projects. 5) We identified factors that appear to be associated with high and low impact. This article presents the key observations of the study and an overview of the methods involved. It has been written for funders of biomedical and health research and health services, health researchers, and policy makers in those fields. It will also be of interest to those involved in research and impact evaluation.
本项目探讨了15至20年前资助的心血管和中风研究所产生的影响，并试图找出与高影响力或低影响力相关的研究、研究人员或环境方面的因素。该项目是一项基于案例研究的综述，涉及1989年至1993年期间在澳大利亚、加拿大和英国资助的29项心血管和中风研究项目。案例研究聚焦于各个项目，但考虑了研究项目从启动到现在所涉及的研究人员和研究思路的发展。通过分层随机选择方法挑选项目，旨在纳入高影响力和低影响力的项目。关键信息如下：1）案例表明，所研究的29个项目产生了广泛多样的影响。2）基础生物医学研究和临床研究产生的影响存在差异。3）知识产出与更广泛的影响之间没有相关性。4）所确定的大多数经济影响来自少数项目。5）我们确定了似乎与高影响力和低影响力相关的因素。本文介绍了该研究的主要观察结果以及所涉及方法的概述。它是为生物医学和健康研究及健康服务的资助者、健康研究人员以及这些领域的政策制定者撰写的。对于参与研究和影响评估的人员来说，它也会有一定的参考价值。
