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[沙门氏菌骨髓炎——骨肿瘤一种罕见的鉴别诊断]

[Salmonella osteomyelitis - a rare differential diagnosis of bone tumors].

作者信息

Ntalos D, Hennes F, Spiro A S, Priemel M, Rueger J M, Klatte T O

机构信息

Klinik und Poliklinik für Unfall-, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.

出版信息

Unfallchirurg. 2017 Jun;120(6):527-530. doi: 10.1007/s00113-016-0307-9.

DOI:10.1007/s00113-016-0307-9
PMID:28083629
Abstract

This case describes a rare salmonella infection suspected to be an osseous lymphoma. A 27-year-old female presented herself with painful swelling of her knee, with prednisolone-treated Crohn's disease as her only pre-existing condition. Salmonella species group C were detected in the osseous material derived from an extraction. The disease was treated with intravenous ceftriaxone, oral cotrimoxazole as well as multiple debridements. The working diagnosis should thus always be questioned and bone pain in patients who are immunosuppressed should be further investigated.

摘要

本病例描述了一例疑似骨淋巴瘤的罕见沙门氏菌感染。一名27岁女性因膝关节疼痛肿胀就诊,其既往病史仅有经泼尼松龙治疗的克罗恩病。从一次抽取的骨材料中检测出C组沙门氏菌。该疾病采用静脉注射头孢曲松、口服复方新诺明以及多次清创治疗。因此,对于工作诊断应始终持怀疑态度,对于免疫抑制患者的骨痛应进一步调查。

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本文引用的文献

1
[Acute hematogenous osteomyelitis in children].
Duodecim. 2014;130(16):1591-8.
2
Imaging of musculoskeletal lymphoma.肌肉骨骼淋巴瘤的影像学检查
Cancer Imaging. 2013 Dec 11;13(4):448-57. doi: 10.1102/1470-7330.2013.0036.
3
Salmonella osteomyelitis: A rare differential diagnosis in osteolytic lesions around the knee.沙门氏菌骨髓炎:膝关节周围溶骨性病变的罕见鉴别诊断。
J Infect Public Health. 2014 Feb;7(1):66-9. doi: 10.1016/j.jiph.2013.07.004. Epub 2013 Sep 5.
4
[Manifestation of osteosarcoma of chronic osteomyelitis: 2 case reports].
Unfallchirurg. 2013 Sep;116(9):854-9. doi: 10.1007/s00113-012-2315-8.
5
Salmonella typhimurium osteomyelitis of the femur in patient with Crohn's disease.患者患有克罗恩病,出现鼠伤寒沙门氏菌致股骨骨髓炎。
Wien Klin Wochenschr. 2010 Jul;122(13-14):437-40. doi: 10.1007/s00508-010-1403-4. Epub 2010 Jul 14.
6
Salmonella osteomyelitis in an immunocompromized patient presenting as a primary lymphoma of the bone.一名免疫功能低下患者的沙门氏菌骨髓炎表现为原发性骨淋巴瘤。
Int J Infect Dis. 2009 Mar;13(2):e67-70. doi: 10.1016/j.ijid.2008.06.030. Epub 2008 Oct 9.
7
Differential diagnosis between osteomyelitis and bone tumors.骨髓炎与骨肿瘤的鉴别诊断。
Acta Radiol. 2008 Oct;49(8):928-33. doi: 10.1080/02841850802241809.
8
Bone tumors and tumorlike conditions: analysis with conventional radiography.骨肿瘤及肿瘤样病变:传统X线摄影分析
Radiology. 2008 Mar;246(3):662-74. doi: 10.1148/radiol.2463061038. Epub 2008 Jan 25.
9
Crohn's disease and discitis.克罗恩病与椎间盘炎。
J R Soc Med. 2004 Oct;97(10):484-5. doi: 10.1177/0141076809701008.
10
Salmonella osteomyelitis in patients with sickle-cell anemia.镰状细胞贫血患者的沙门氏菌骨髓炎。
N Engl J Med. 1957 Aug 29;257(9):403-7. doi: 10.1056/NEJM195708292570904.