Dey Nilanjan, Samanta Suman K, Bhattacharya Santanu
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560012, India.
Chem Commun (Camb). 2017 Jan 26;53(9):1486-1489. doi: 10.1039/c6cc08657h.
Oligo(p-phenylenevinylene) based bis-pyridinium derivatives show 'ratiometric' detection of heparin in water. For the first time, we present a dose-dependent, multi-color emission switching in the presence of heparin. The reversible self-assembly of probes with heparin as the stimulus is also exploited for the screening of heparinase I enzyme.
基于对苯撑乙烯撑的双吡啶鎓衍生物在水中对肝素呈现“比率”检测。我们首次展示了在肝素存在下的剂量依赖性多色发射切换。还利用以肝素为刺激物的探针可逆自组装来筛选肝素酶I。
