Gehlen M, Lazarescu A D, Hinz C, Boncu B, Schmidt N, Pfeifer M, Schwarz-Eywill M, Pollähne W, Minne H W
Osteologisches Schwerpunkt- und Forschungszentrum DVO, Klinik Der FÜRSTENHOF, Fachklinik für Rheumatologie, Orthopädie und Osteologie, Am Hylligen Born 7, 31812, Bad Pyrmont, Deutschland.
Z Rheumatol. 2017 Apr;76(3):274-278. doi: 10.1007/s00393-016-0259-z.
Pregnancy and lactation-associated osteoporosis (PLO) is a rare form of osteoporosis, which occurs in the last trimester or postpartum. So far 100 cases have been published. The leading symptoms are severe low back pain or less frequently hip pain. Many patients develop postpartum depression due to inability to care for the baby and vertebral fractures. The therapeutic decision has to be made individually but teriparatid and bisphosphonates seem to be the best option. We report the clinical course (16 years) of a 37-year-old patient with PLO, who suffered 6 vertebral fractures. There were severe physical limitations and mental problems caused by the disease. The patient was treated by multimodal therapy including physiotherapy and psychotherapy and bisphosphonates were given. The time between the onset of symptoms and diagnosis was 5 months. No further fractures occurred in the following 16 years. The physical and mental condition significantly improved.
妊娠和哺乳期骨质疏松症（PLO）是一种罕见的骨质疏松症形式，发生在妊娠晚期或产后。迄今为止，已发表了100例病例。主要症状是严重的腰痛，较少见的是髋部疼痛。许多患者因无法照顾婴儿和发生椎体骨折而出现产后抑郁。治疗决策必须个体化，但特立帕肽和双膦酸盐似乎是最佳选择。我们报告了一名37岁PLO患者的临床病程（16年），该患者发生了6次椎体骨折。疾病导致了严重的身体限制和心理问题。该患者接受了包括物理治疗、心理治疗和双膦酸盐治疗在内的多模式治疗。症状出现到诊断的时间为5个月。在接下来的16年中未再发生骨折。身体和心理状况显著改善。
