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用于替代骨骼和牙齿的新型复合材料钛/玻璃陶瓷表面的组织。

Tissues at the surface of the new composite material titanium/glass-ceramic for replacement of bone and teeth.

作者信息

Müller-Mai C, Schmitz H J, Strunz V, Fuhrmann G, Fritz T, Gross U M

机构信息

Institute of Pathology, Steglitz University Hospital, Free University, Berlin, Federal Republic of Germany.

出版信息

J Biomed Mater Res. 1989 Oct;23(10):1149-68. doi: 10.1002/jbm.820231005.

Abstract

A new composite implant material titanium/glass-ceramic was tested in rabbits using light microscopy, histomorphometry, and biomechanical testing methods. Two rabbit implant models were used. The first premolar tooth was replaced and cylinders inserted into the trabecular bone of the distal femur below the patella sliding plane. There was bone bonding to the glass-ceramic component and additional mechanical interlocking, due to bone ingrowth between the titanium matrix into secondary pores. This was proved by measuring the tensile strength at the interface of the new composite material which was in the same range as compared to pure glass-ceramic implants. In tooth replacement there was a tight attachment of gingival epithelium and stroma to composite titanium/glass-ceramic. These results are of particular clinical interest: physicochemical bone bonding and additional mechanical interlocking result in a resistance of the implant material against shear and tensile loads at the interface. Therefore this new composite material should be suitable for further load-bearing applications.

摘要

一种新型复合植入材料钛/玻璃陶瓷在兔子身上进行了测试,采用了光学显微镜、组织形态计量学和生物力学测试方法。使用了两种兔子植入模型。第一前磨牙被替换,圆柱体被插入髌骨滑动平面下方股骨远端的小梁骨中。由于钛基体中的二次孔隙之间有骨长入,骨与玻璃陶瓷成分发生了骨结合并产生了额外的机械互锁。通过测量新型复合材料界面处的拉伸强度得到了证明,其与纯玻璃陶瓷植入物相比处于相同范围内。在牙齿替换中,牙龈上皮和基质与复合钛/玻璃陶瓷紧密附着。这些结果具有特殊的临床意义:物理化学骨结合和额外的机械互锁导致植入材料在界面处抵抗剪切和拉伸载荷。因此,这种新型复合材料应该适用于进一步的承重应用。

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