Naselli Aldo, Bishop Hugh, Walker Shonagh, Warris Adilia
a Division of Paediatric Infections Disease , Royal Aberdeen Children's Hospital , Aberdeen , UK.
b Division of Paediatric Haemato-Oncology , Royal Aberdeen Children's Hospital , Aberdeen , UK.
Pediatr Hematol Oncol. 2017 Feb;34(1):24-28. doi: 10.1080/08880018.2016.1265034. Epub 2017 Jan 13.
Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder without the presence of gallstones. In children with malignancies or chemotherapy-induced neutropenia, AAC is very rare. Clinical diagnosis of AAC remains difficult in this patient population but an early recognition followed by an appropriate intervention may confer a benefit. Only three pediatric patients with underlying hematological malignancies whose clinical treatment course was complicated by the development of AAC have been described. We describe a neutropenic pediatric patient who developed AAC following chemotherapy for acute T-cell acute lymphoblastic leukemia (T-ALL), which was successfully managed with conservative treatment.
AAC: Acute acalculous cholecystitis; T-ALL: T-cell acute lymphoblastic leukemia; TPN: Total parenteral nutrition.
急性非结石性胆囊炎（AAC）是一种不存在胆结石的胆囊炎症。在患有恶性肿瘤或化疗引起的中性粒细胞减少症的儿童中，AAC非常罕见。在这类患者群体中，AAC的临床诊断仍然困难，但早期识别并随后进行适当干预可能有益。仅有3例患有潜在血液系统恶性肿瘤且临床治疗过程因AAC的发生而复杂化的儿科患者被描述过。我们描述了一名中性粒细胞减少的儿科患者，其在接受急性T细胞急性淋巴细胞白血病（T-ALL）化疗后发生了AAC，并通过保守治疗成功治愈。
AAC：急性非结石性胆囊炎；T-ALL：T细胞急性淋巴细胞白血病；TPN：全胃肠外营养
