de Zubicaray Greig, Fraser Douglas, Ramajoo Kori, McMahon Katie
Faculty of Health and Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, Australia.
School of Public Health, University of Queensland, Brisbane, Australia.
Neuropsychologia. 2017 Feb;96:78-88. doi: 10.1016/j.neuropsychologia.2017.01.010. Epub 2017 Jan 10.
Few investigations of lexical access in spoken word production have investigated the cognitive and neural mechanisms involved in action naming. These are likely to be more complex than the mechanisms involved in object naming, due to the ways in which conceptual features of action words are represented. The present study employed a blocked cyclic naming paradigm to examine whether related action contexts elicit a semantic interference effect akin to that observed with categorically related objects. Participants named pictures of intransitive actions to avoid a confound with object processing. In Experiment 1, body-part related actions (e.g., running, walking, skating, hopping) were named significantly slower compared to unrelated actions (e.g., laughing, running, waving, hiding). Experiment 2 employed perfusion functional Magnetic Resonance Imaging (fMRI) to investigate the neural mechanisms involved in this semantic interference effect. Compared to unrelated actions, naming related actions elicited significant perfusion signal increases in frontotemporal cortex, including bilateral inferior frontal gyrus (IFG) and hippocampus, and decreases in bilateral posterior temporal, occipital and parietal cortices, including intraparietal sulcus (IPS). The findings demonstrate a role for temporoparietal cortex in conceptual-lexical processing of intransitive action knowledge during spoken word production, and support the proposed involvement of interference resolution and incremental learning mechanisms in the blocked cyclic naming paradigm.
很少有关于口语单词生成中词汇通达的研究考察了动作命名所涉及的认知和神经机制。由于动作词概念特征的表征方式，这些机制可能比物体命名所涉及的机制更为复杂。本研究采用了一种分组循环命名范式，以检验相关动作情境是否会引发一种类似于在类别相关物体中观察到的语义干扰效应。参与者对不及物动作的图片进行命名，以避免与物体加工产生混淆。在实验1中，与身体部位相关的动作（如跑步、行走、滑冰、跳跃）的命名速度明显慢于不相关动作（如大笑、跑步、挥手、躲藏）。实验2采用灌注功能磁共振成像（fMRI）来研究这种语义干扰效应所涉及的神经机制。与不相关动作相比，命名相关动作在额颞叶皮层引发了显著的灌注信号增加，包括双侧额下回（IFG）和海马体，而在双侧后颞叶、枕叶和顶叶皮层，包括顶内沟（IPS），灌注信号则减少。研究结果表明，颞顶叶皮层在口语单词生成过程中对不及物动作知识的概念-词汇加工中发挥作用，并支持了在分组循环命名范式中干扰解决和增量学习机制的参与。
